1,3-Bis(4-bromophenyl)-1H-pyrazol-5-amine CAS 618098-21-8
| CAS No. | 618098-21-8 |
| Molecular Formula | C15H11Br2N3 |
| Molecular Weight | 393.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1,3-Bis(4-bromophenyl)-1H-pyrazol-5-amine (CAS 618098-21-8) is a high-purity analytical reference standard with the molecular formula C15H11Br2N3 and a molecular weight of 393.08 g/mol.
The molecular framework of 1,3-Bis(4-bromophenyl)-1H-pyrazol-5-amine (C15H11Br2N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H11Br2N3 |
| Molecular Weight | 393.08 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related Bis Standards
- 1,4-Bis(4-bromophenyl)-1H-pyrazol-5-amine (CAS 1202028-75-8)
- 1-(4-bromophenyl)-4-(iodomethyl)-7-oxabicyclo[2.2.1]heptane (CAS 1477524-76-7)
- 3-(4-Bromophenyl)-5-((phenylselanyl)methyl)isoxazole (CAS 833462-31-0)
- 1-(4-Bromophenyl)-4-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]quinoxaline (CAS 338968-40-4)
- 6-(3-((4-Bromophenyl)sulfonyl)ureido)hexanoic acid (CAS 2044702-76-1)
- 4-((4-Bromophenyl)sulfonyl)-N-methyl-2-phenyloxazol-5-amine (CAS 823828-25-7)
- Ethyl 4-(4-bromophenyl)-2-(2-cyanoacetamido)thiophene-3-carboxylate (CAS 546064-73-7)
- (2-Bromophenyl)(2-((2-fluorobenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)methanone (CAS 851806-96-7)
Recommended Standards
- 4-(2,5-Difluoro-4-nitrophenoxy)-3-iodopyridin-2-amine (CAS 1345854-92-3)
- 3,4-Dichloro-N-[2,4-dichloro-5-(propan-2-yloxy)phenyl]benzamide (CAS 338961-14-1)
- 4-(2,4-Dichlorophenoxy)-N-(3,5-dichlorophenyl)butanamide (CAS 303091-87-4)
- 8-(Benzyloxy)-5,7-dibromoquinoline (CAS 84165-50-4)
- 5,6-Dihydro-7H-pyrrolo[1,2-c]imidazol-7-one (CAS 426219-43-4)
- 1-(Pyridin-4-yl)azetidin-3-ol (CAS 1339844-82-4)
- 3,5-Dichloro-4-methylthioanisole (CAS 1803837-22-0)
- 1-(3-Fluoro-5-(isopentyloxy)phenyl)propan-1-one (CAS 1443342-96-8)
- Bis(2-methoxyethyl) diazene-1,2-dicarboxylate (CAS 940868-64-4)
- Methyl 3-(benzyloxy)-4-oxo-4H-pyran-2-carboxylate (CAS 1332855-89-6)
- Ethyl 2-imino-3-oxobutanoate (CAS 678992-87-5)
- 2-Chloro-4-(4-methylpiperazin-1-yl)pyrimidine (CAS 749898-92-8)
- 2-Bromo-5-(difluoromethyl)-4-fluoronicotinaldehyde (CAS 1806904-77-7)
- Acetyl-(Leu28·31)-Neuropeptide Y (24-36) (CAS 155709-24-3)
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