7-(Trifluoromethyl)-4h,5h,6h,7h-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid CAS 869948-09-4
| CAS No. | 869948-09-4 |
| Molecular Formula | C8H8F3N3O2 |
| Molecular Weight | 235.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 7-(Trifluoromethyl)-4h,5h,6h,7h-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 7-(Trifluoromethyl)-4h,5h,6h,7h-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 869948-09-4), a certified reference material (molecular formula C8H8F3N3O2, MW 235.16 g/mol) for analytical method development and quality control.
The molecular framework of 7-(Trifluoromethyl)-4h,5h,6h,7h-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (C8H8F3N3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H8F3N3O2 |
| Molecular Weight | 235.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Trifluoromethyl Standards
- 3-(Trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine-1-carboxylic acid (CAS 1535990-71-6)
- 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridine-7-carboxylic acid (CAS 1620564-62-6)
- 2-((6-Methyl-4-(trifluoromethyl)pyridin-2-yl)oxy)acetic acid (CAS 1713476-76-6)
- 3-(2-Oxo-5-(trifluoromethyl)pyridin-1(2H)-yl)propanoic acid (CAS 175277-72-2)
- 4-(Trifluoromethyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-6-carboxylic acid (CAS 1784701-58-1)
- 2-(2-Oxo-5-(trifluoromethyl)pyridin-1(2h)-yl)acetohydrazide (CAS 314768-14-4)
- 7-(Trifluoromethyl)-4h,5h,6h,7h-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (CAS 869948-08-3)
- 2,4-Bis(trifluoromethyl)cyclohexanamine (CAS 65934-73-8)
Recommended Standards
- 5-Nitro-2-(1h-1,2,3,4-tetrazol-1-yl)benzoic acid (CAS 926199-53-3)
- 4-Methoxy-2-(trifluoromethoxy)benzamide (CAS 886502-47-2)
- Cis-2-(2-bromopropan-2-yl)-5-isopropyltetrahydrofuran (CAS 89065-45-2)
- 4-ethoxy-1-nitro-2-(trifluoromethyl)benzene (CAS 363-96-2)
- rac-3-Octadecanamido-2-Ethoxypropan-1-ol Phosphocholine (CAS 112989-02-3)
- (3-Amino-5-chloro-6-methoxypyridin-2-yl)methanol (CAS 2644018-73-3)
- 2-Chloro-3-methoxybenzyl bromide (CAS 354138-68-4)
- Methyl 2-cyclopentylideneacetate (CAS 40203-73-4)
- 1-Ethyl-1,2,3,4-tetrahydroquinoline-8-carboxylic acid (CAS 689162-91-2)
- 2-({2-[4-(3,4-Dimethylanilino)-4-oxobutanoyl]hydrazino}carbonyl)cyclohexanecarboxylic acid (CAS 900596-59-0)
- 2-(2-Ethylphenoxy)-4-methylaniline (CAS 946728-92-3)
- 4-Methyl-2-(4-nitro-1,3-dioxoisoindolin-2-yl)pentanoic acid (CAS 18635-95-5)
- (R)-3-Amino-2-(4-bromophenyl)propanoic acid (CAS 1442114-70-6)
- Des-[Ser]8-Liraglutide (CAS CATO-C4X-199233)
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