2,4-Bis(trifluoromethyl)cyclohexanamine CAS 65934-73-8
| CAS No. | 65934-73-8 |
| Molecular Formula | C8H11F6N |
| Molecular Weight | 235.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,4-Bis(trifluoromethyl)cyclohexanamine (CAS 65934-73-8), molecular formula C8H11F6N and molecular weight 235.17 g/mol, is a CATO reference standard with documented purity and traceability.
2,4-Bis(trifluoromethyl)cyclohexanamine (C8H11F6N) contains fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H11F6N |
| Molecular Weight | 235.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Bis Standards
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- 3-(Trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine-1-carboxylic acid (CAS 1535990-71-6)
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- 2-((6-Methyl-4-(trifluoromethyl)pyridin-2-yl)oxy)acetic acid (CAS 1713476-76-6)
- 3-(2-Oxo-5-(trifluoromethyl)pyridin-1(2H)-yl)propanoic acid (CAS 175277-72-2)
- 4-(Trifluoromethyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-6-carboxylic acid (CAS 1784701-58-1)
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Recommended Standards
- (4-Amino-3-(difluoromethoxy)phenyl)dimethylphosphine oxide (CAS 2903922-86-9)
- (2-Amino-5-(difluoromethoxy)phenyl)dimethylphosphine oxide (CAS 2750028-82-9)
- 5-Fluoro-1-picolinoylpyrimidine-2,4(1H,3H)-dione (CAS 88740-57-2)
- 2-Amino-5-(pentafluoro-λ6-sulfanyl)phenol (CAS 1159512-48-7)
- 1-[(3,4-Dichlorophenyl)methyl]-4-nitro-1h-pyrazole (CAS 333444-52-3)
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- 2-Bromo-5-hydroxy-4-methylbenzoic acid (CAS 1195323-34-2)
- 2,2-Dichloro-N-(1-(5-nitrofuran-2-yl)-1H-1,2,3-triazol-4-yl)acetamide (CAS 64082-38-8)
- 6-Amino-4-(4-methoxyphenyl)-3-methyl-1-(p-tolyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile (CAS 300701-99-9)
- 2-(3-Hydroxy-5-methyl-4H-pyrazol-4-yl)acetamide (CAS 99357-27-4)
- Methyl (6-bromopyridin-3-yl)carbamate (CAS 1209459-81-3)
- 5-((2,4-Difluorophenyl)imino)furan-2(5H)-one (CAS 6954-66-1)
- 2,7,8-Trimethyl-2-(4,8,12-trimethyltridecyl)chroman-6-ol (CAS 7616-22-0)
- Liraglutide Impurity 10 TFA Salt (CAS CATO-C4X-199210)
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