Entecavir 4-Dimethylsilyl USP Impurity CAS 870614-82-7

Description

The occurrence of Entecavir 4-Dimethylsilyl USP Impurity is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Entecavir 4-Dimethylsilyl USP Impurity (CAS 870614-82-7), a pharmacopoeial impurity reference standard (molecular formula C14H21N5O3Si, MW 335.43 g/mol) used for the identification and quantification of trace impurities in APIs.

Based on its molecular formula C14H21N5O3Si, Entecavir 4-Dimethylsilyl USP Impurity contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 335.43 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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