Evocalcet Impurity 40 CAS 870964-69-5
| CAS No. | 870964-69-5 |
| Molecular Formula | C24H26N2O2 |
| Molecular Weight | 374.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Evocalcet Impurity 40 (C24H26N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Evocalcet Impurity 40 (CAS 870964-69-5) is a certified pharmaceutical impurity reference standard with the molecular formula C24H26N2O2 and a molecular weight of 374.48 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H26N2O2 |
| Molecular Weight | 374.48 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 2 |
Related Evocalcet Standards
- Evocalcet (CAS 870964-67-3)
- Evocalcet Impurity 14 (CAS 870964-68-4)
- Evocalcet Impurity 34 (CAS CATO-C4X-248534)
- Evocalcet Impurity 42 (CAS 2851537-33-0)
- Evocalcet Impurity 7 (CAS CATO-C4X-24857)
- Evocalcet Impurity 8 (CAS CATO-C4X-24858)
- Evocalcet Impurity 9 (CAS CATO-C4X-24859)
- Evocalcet Impurity 36 (CAS 2851537-35-2)
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