5-Bromo-3-(1-(ethylsulfonyl)piperidin-4-yl)-2H-indazole-7-carbonitrile CAS 872350-26-0
| CAS No. | 872350-26-0 |
| Molecular Formula | C15H17BrN4O2S |
| Molecular Weight | 397.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-Bromo-3-(1-(ethylsulfonyl)piperidin-4-yl)-2H-indazole-7-carbonitrile (C15H17BrN4O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
5-Bromo-3-(1-(ethylsulfonyl)piperidin-4-yl)-2H-indazole-7-carbonitrile (CAS 872350-26-0) is a high-purity analytical reference standard with the molecular formula C15H17BrN4O2S and a molecular weight of 397.29 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Bromo-3-(1-(ethylsulfonyl)piperidin-4-yl)-2H-indazole-7-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H17BrN4O2S |
| Molecular Weight | 397.29 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- Apixaban impurity 158 (CAS 148476-97-5)
- (Z)-3-(3-Bromophenyl)-2-(4-(4-methoxyphenyl)thiazol-2-yl)acrylonitrile (CAS 476670-29-8)
- 2'-Hydroxy-3'-methoxyacetophenone (CAS 703-98-0)
- Tert-butyl 2-(aminomethyl)-5,7-dihydro-6H-pyrrolo[3,4-b]pyridine-6-carboxylate (CAS 2387596-79-2)
- 4-(5-(1-Hydroxyethyl)-4-methylpyridin-2-yl)piperazine-1-carbaldehyde (CAS 1355229-38-7)
- Rupatadine impurity 9 (CAS 41711-38-0)
- (2e)-3-(2-Chloropyridin-3-yl)prop-2-enoic acid (CAS 118419-93-5)
- 1-Aminonaphthalene-2-boronic acid (CAS 1621965-01-2)
- 5-(Aminomethyl)thiophene-2-carbonitrile Hydrochloride (CAS 172349-10-9)
- 3-Chloro-6-(3,4-dimethylphenyl)pyridazine (CAS 64262-73-3)
- Argatroban Impurity 36 (CAS CATO-C4X-100736)
- Cycloaspeptide A (CAS 109171-13-3)
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