Netupitant Impurity N3 CAS 873443-69-7
| CAS No. | 873443-69-7 |
| Molecular Formula | C18H19ClN4 |
| Molecular Weight | 326.82 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, Netupitant Impurity N3 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 326.82 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Netupitant Impurity N3 (CAS 873443-69-7), a pharmacopoeial impurity reference standard (molecular formula C18H19ClN4, MW 326.82 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Netupitant Impurity N3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H19ClN4 |
| Molecular Weight | 326.82 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Netupitant Standards
- Netupitant Impurity 60 (CAS CATO-C4X-122360)
- Netupitant Impurity 4 (CAS CATO-C4X-12234)
- Netupitant Impurity 47 (CAS CATO-C4X-122347)
- Netupitant Impurity 7 (CAS CATO-C4X-12237)
- Netupitant Impurity 36 (CAS CATO-C4X-122336)
- Netupitant Impurity 46 (CAS CATO-C4X-122346)
- Netupitant Impurity 33 (CAS CATO-C4X-122333)
- Netupitant Impurity 26 (CAS CATO-C4X-122326)
Recommended Standards
- N-{[2-chloro-6-(3-methyl-1H-indol-1-yl)phenyl]methyl}propanamide (CAS 866042-90-2)
- rac- Etomoxir (CAS 82258-36-4)
- Ethyl 8-(4-chloro-2-methoxyphenyl)-8-oxooctanoate (CAS 951886-65-0)
- S-(-)-Etomoxir (CAS 828934-40-3)
- Itraconazole Impurity 100 (CAS CATO-C4X-1497100)
- Cefpodoxime Impurity 63 (CAS CATO-C4X-157963)
- Hydroxychloroquine Impurity 70 (CAS 56881-09-5)
- Methyl 4'-(chlorosulfonyl)-[1,1'-biphenyl]-3-carboxylate (CAS 939761-08-7)
- 4-Chloro-1-ethynyl-2-nitrobenzene (CAS 947513-49-7)
- 3-(6-Amino-8-mercapto-9H-purin-9-yl)-2-oxopropanal (CAS 69400-33-5)
- N-methyl-1-(3-(thiophen-2-yl)phenyl)methanamine (CAS 859833-20-8)
- Thiophene,3,4-diethynyl- (9CI) (CAS 138354-60-6)
- Opicapone Impurity 56 (CAS CATO-C4X-240456)
- Pancreatic Polypeptide (1-17)-(Ala31,Aib32)-Neuropeptide Y (18-36) (human) trifluoroacetate salt (CAS 313988-70-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com