Netupitant Impurity 60 CAS CATO-C4X-122360
| CAS No. | CATO-C4X-122360 |
| Molecular Formula | C19H26N4O |
| Molecular Weight | 326.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Netupitant Impurity 60 (CAS CATO-C4X-122360, C19H26N4O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Netupitant Impurity 60 (C19H26N4O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Netupitant Impurity 60 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H26N4O |
| Molecular Weight | 326.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Netupitant Standards
- Netupitant Impurity 4 (CAS CATO-C4X-12234)
- Netupitant Impurity 47 (CAS CATO-C4X-122347)
- Netupitant Impurity 7 (CAS CATO-C4X-12237)
- Netupitant Impurity N3 (CAS 873443-69-7)
- Netupitant Impurity 36 (CAS CATO-C4X-122336)
- Netupitant Impurity 46 (CAS CATO-C4X-122346)
- Netupitant Impurity 33 (CAS CATO-C4X-122333)
- Netupitant Impurity 26 (CAS CATO-C4X-122326)
Recommended Standards
- N-Cyclohexyl-5-propyl-1-(p-tolyl)-1H-1,2,3-triazole-4-carboxamide (CAS 950231-55-7)
- Relebactam Impurity 71 (CAS CATO-C4X-214471)
- N,N-Diethyl-3-(4-methyl-5-sulfanyl-4H-1,2,4-triazol-3-yl)benzene-1-sulfonamide (CAS 571153-14-5)
- Relebactam Impurity 73 (CAS CATO-C4X-214473)
- Dabrafenib Impurity N1 (CAS 1195765-47-9)
- Safinamide Impurity 59 (CAS CATO-C4X-159059)
- Cefuroxime Impurity 31 (CAS CATO-C4X-124531)
- 2-(3-Chlorobut-3-en-1-yl)-1,1'-biphenyl (CAS 951890-02-1)
- (R)-Ethyl 4,4,4-trifluoro-3-hydroxybutanoate (CAS 85571-85-3)
- 4-Iodo-5-(m-tolyl)-1H-pyrazol-3-amine (CAS 501100-29-4)
- 5-(Benzyloxy)-2-chloro-4-(trifluoromethyl)phenylboronic acid (CAS 2377608-74-5)
- (1<I>S</I>,2<I>S</I>)-<I>N</I>-<I>p</I>-Tosyl-1,2-dimesitylethylenediamine (CAS 1293946-41-4)
- 6-Chloro-2-methyl-N-propylpyrimidin-4-amine (CAS 261765-60-0)
- Semaglutide impurity 215 (CAS CATO-C4X-2226215)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com