4-Amino-5-aminomethyl-2-methylpyrimidine dihydrochloride CAS 874-43-1
| CAS No. | 874-43-1 |
| Molecular Formula | C6H10N4 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-Amino-5-aminomethyl-2-methylpyrimidine dihydrochloride (CAS 874-43-1), a certified reference material (molecular formula C6H10N4HCl, MW 174.63 g/mol) for analytical method development and quality control.
The molecular framework of 4-Amino-5-aminomethyl-2-methylpyrimidine dihydrochloride (C6H10N4HCl) is characterized by a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Amino-5-aminomethyl-2-methylpyrimidine dihydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H10N4 2*HCl |
| Molecular Weight | 174.63 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Amino Standards
- 3-Amino-1-methyl-4-phenoxyindazole (CAS 1000018-07-4)
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- Methyl 2-amino-5-bromo-4-isopropylbenzoate (CAS 1000018-13-2)
- Methyl 2-amino-3-(pyridin-2-yl)propanoate (CAS 100002-84-4)
- 100005-23-0 2-Amino-4-(4-methoxyphenyl)-5-methylthiophene-3-carbonitrile 7050AC C13H12N2OS (CAS 100005-23-0)
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Recommended Standards
- 1-(4-Methyl-2-(((tetrahydrofuran-2-yl)methyl)imino)-2,3-dihydrothiazol-5-yl)ethan-1-one (CAS 850023-39-1)
- 5-(Benzo[d]thiazol-2-yl)thiophene-2-carbonyl chloride (CAS 1706462-04-5)
- 1-Benzyl 4-methyl 2-(trifluoromethyl)piperidine-1,4-dicarboxylate (CAS 2306271-78-1)
- 6-Bromo-2-methyl-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 221311-16-6)
- 3-Hydroxy-6,6-dimethyl-2-methylenebicyclo[3.1.1]heptane (CAS 5947-36-4)
- 1-(Neopentylamino)-3-phenoxypropan-2-ol (CAS 1281023-89-9)
- 8-Hydroxy-N-(3-(imidazo[1,2-a]pyridin-2-yl)phenyl)-2-oxo-2H-chromene-3-carboxamide (CAS 1170689-68-5)
- 2-Carbamoyl-5-fluorobenzoic Acid (CAS 1310532-40-1)
- 4-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)isophthalic acid (CAS 500533-95-9)
- Tirzepatide Impurity 44 (CAS CATO-C4X-324044)
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