2,3,6-Trichloropyridin-4-amine CAS 874491-78-8
| CAS No. | 874491-78-8 |
| Molecular Formula | C5H3Cl3N2 |
| Molecular Weight | 197.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2,3,6-Trichloropyridin-4-amine (CAS 874491-78-8), a certified reference material (molecular formula C5H3Cl3N2, MW 197.45 g/mol) for analytical method development and quality control.
2,3,6-Trichloropyridin-4-amine (C5H3Cl3N2) contains a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 2,3,6-Trichloropyridin-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H3Cl3N2 |
| Molecular Weight | 197.45 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Trichloropyridin Standards
- 3,5,6-Trichloropyridin-2-amine (CAS 1378670-79-1)
- 2,4,5-Trichloropyridin-3-amine (CAS 173435-47-7)
- 2,4,6-Trichloropyridin-3-amine (CAS 91872-08-1)
- 2,5,6-Trichloropyridin-3-amine (CAS 55304-76-2)
- 3,4,5-Trichloropyridin-2-amine (CAS 55933-91-0)
- 2,3,5-Trichloropyridin-4-amine (CAS 28443-69-8)
- 3,4,5-Trichloropyridin-2(3H)-one (CAS 1822711-95-4)
- 2,3,5-Trichloropyridin-4-ol (CAS 1970-40-7)
Recommended Standards
- 3,5-Dichloro-2-(chloromethyl)pyrazine (CAS 1824441-19-1)
- 2,4,5-Trichloro-6-methylpyrimidine (CAS 6554-69-4)
- 2-chloro-4-(dichloromethyl)pyrimidine (CAS 1803566-44-0)
- 2,4,6-Trichloro-5-methylpyrimidine (CAS 1780-36-5)
- n-(5-Methylisoxazol-3-yl)benzenesulfonamide (CAS 13053-79-7)
- 2-[6-(4-Ethoxyphenyl)imidazo[2,1-b][1,3]thiazol-3-yl]acetic acid (CAS 891752-37-7)
- 2-(1,3-Dimethyl-1h-1,2,4-triazol-5-yl)-2-phenylethan-1-amine (CAS 1344069-37-9)
- 1-(4-Hydroxy-7-phenylthieno[3,2-d]pyrimidin-2-yl)-N-(2-(piperidin-1-yl)ethyl)piperidine-3-carboxamide (CAS 1242876-29-4)
- 4-[[[4-[(4-bromo-2-fluorophenyl)amino]-6-methoxy-7-quinazolinyl]oxy]methyl]-1-Piperidinecarboxylic acid 1,1-dimethylethyl ester (CAS 338992-20-4)
- 2-(4-(Methylsulfonyl)phenyl)morpholine (CAS 1097797-22-2)
- [2-(1-Amino-2-methyl-propyl)-pyridin-4-yl]-carbamic acid tert-butyl ester (CAS 2352847-24-4)
- 4-Fmoc-3(R)-morpholine carboxylic acid (CAS 942153-03-9)
- 1,1,3,3-Tetrakis((trifluoromethyl)sulfonyl)propane (CAS 60805-11-0)
- Des-Ser39-Tirzepatide (CAS CATO-CPTD788936)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com