5-Chloro-2-fluoro-4-methylbenzenesulfonamide CAS 874801-54-4
| CAS No. | 874801-54-4 |
| Molecular Formula | C7H7ClFNO2S |
| Molecular Weight | 223.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Chloro-2-fluoro-4-methylbenzenesulfonamide (C7H7ClFNO2S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
5-Chloro-2-fluoro-4-methylbenzenesulfonamide (CAS 874801-54-4), molecular formula C7H7ClFNO2S and molecular weight 223.65 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Chloro-2-fluoro-4-methylbenzenesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H7ClFNO2S |
| Molecular Weight | 223.65 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- N-(2-chloro-4-fluorophenyl)methanesulfonamide (CAS 1001026-51-2)
- (4-Chloro-2-fluorophenyl)methanesulfonamide (CAS 1001026-53-4)
- 4-Chloro-2-fluoro-n-methylbenzenesulfonamide (CAS 1089634-90-1)
- n-(4-Chloro-3-fluorophenyl)methanesulfonamide (CAS 1097107-44-2)
- 2-Chloro-4-fluoro-n-methylbenzenesulfonamide (CAS 1098391-40-2)
- 3-Chloro-2-fluoro-n-methylbenzenesulfonamide (CAS 1099029-88-5)
- 2-Chloro-4-fluoro-5-methylbenzene-1-sulfonamide (CAS 1208077-19-3)
- 5-Chloro-4-fluoro-2-methylbenzenesulfonamide (CAS 1242339-14-5)
Recommended Standards
- 3-Chloro-5-fluoro-2-methylbenzenesulfonamide (CAS 306937-31-5)
- Chloromethyl 2-((tert-butoxycarbonyl)amino)acetate (CAS 34573-36-9)
- 2-(2-Chloro-2-nitropropoxy)tetrahydro-2H-pyran (CAS 86958-48-7)
- N-(3-chloro-4-fluorophenyl)methanesulfonamide (CAS 71270-60-5)
- rac-2-{4-[(3R,4R)-1-[(tert-butoxy)carbonyl]-4-methoxypyrrolidin-3-yl]-1H-1,2,3-triazol-1-yl}acetic acid (CAS 1989638-26-7)
- 2-Methyl-5-oxo-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidine-6-carboxylic acid (CAS 446829-82-9)
- Ethyl 2-amino-3-(piperidin-1-yl)propanoate (CAS 745776-88-9)
- 4-Isopropylbenzyl 2-(4-piperidinyl)ethyl etherhydrochloride (CAS 1219971-74-0)
- 2,4-Dichloro-8-methoxyquinoline-3-carbonitrile (CAS 2768871-93-6)
- {2-[4-(2-methoxyethyl)-4H-1,2,4-triazol-3-yl]ethyl}amine hydrochloride (CAS 1262774-52-6)
- 3-amino-2-methyl-propanenitrile (CAS 96-16-2)
- 4-(Phenylmethoxy)benzenecarboximidamide (CAS 31066-05-4)
- 6-(Pyridin-2-yl)-1,3,5-triazine-2,4(1H,3H)-dione (CAS 116670-76-9)
- Cyclolinopeptide B (CAS 193139-41-2)
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