1-(3,5-Difluorobenzoyl)piperazine CAS 874942-08-2
| CAS No. | 874942-08-2 |
| Molecular Formula | C11H12F2N2O |
| Molecular Weight | 226.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(3,5-Difluorobenzoyl)piperazine (C11H12F2N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 1-(3,5-Difluorobenzoyl)piperazine (CAS 874942-08-2), a certified reference material (molecular formula C11H12F2N2O, MW 226.22 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H12F2N2O |
| Molecular Weight | 226.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluorobenzoyl Standards
- 1-(2,5-Difluorobenzoyl)piperazine (CAS 179334-11-3)
- 1-(2,6-Difluorobenzoyl)piperazine (CAS 179334-15-7)
- 1-(2,4-Difluorobenzoyl)piperazine (CAS 926209-09-8)
- 1-(3,4-Difluorobenzoyl)piperazine (CAS 923237-42-7)
- 4-(2,3-Difluorobenzoyl)piperidine (CAS 1388035-56-0)
- 3-(2,4-Difluorobenzoyl)thiophene (CAS 898771-60-3)
- 3-(3,4-Difluorobenzoyl)-4-methylpyridine (CAS 1187163-84-3)
- 2-(2,6-Difluorobenzoyl)-5-methylpyridine (CAS 1187164-66-4)
Recommended Standards
- 1-(3,4-dimethylphenyl)-4,4-difluorobutane-1,3-dione (CAS 832740-29-1)
- 1-(3,5-Difluorophenyl)cyclopentanecarboxylic Acid (CAS 610791-42-9)
- 1-(3,4-Difluorophenyl)cyclopentanecarboxylic Acid (CAS 741682-84-8)
- 1-(4-ethylphenyl)-4,4-difluorobutane-1,3-dione (CAS 832741-19-2)
- 2-(tert-Butoxycarbonyl)-5-oxa-2-azaspiro[3.4]octane-7-carboxylic acid (CAS 1251009-46-7)
- Oxazole, 2,2′-[(1S)-6,6′-dimethyl[1,1′-biphenyl]-2,2′-diyl]bis[4,5-dihydro-4-(phenylmethyl)-, (4S,4′S)- (CAS 302342-92-3)
- 2-(3-Chlorophenyl)-5-((2,6-dimethylmorpholino)methyl)benzo[d]oxazole (CAS 1706453-04-4)
- 2-{[(2S)-4-azidobutan-2-yl]oxy}oxane (CAS 1807919-90-9)
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