Ethyl 1-benzyl-4-(2-fluorophenyl)pyrrolidine-3-carboxylate CAS 874990-49-5
| CAS No. | 874990-49-5 |
| Molecular Formula | C20H22FNO2 |
| Molecular Weight | 327.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 1-benzyl-4-(2-fluorophenyl)pyrrolidine-3-carboxylate.
Ethyl 1-benzyl-4-(2-fluorophenyl)pyrrolidine-3-carboxylate (CAS 874990-49-5), molecular formula C20H22FNO2 and molecular weight 327.39 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Ethyl 1-benzyl-4-(2-fluorophenyl)pyrrolidine-3-carboxylate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 327.39 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Ethyl 1-benzyl-4-(2-fluorophenyl)pyrrolidine-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H22FNO2 |
| Molecular Weight | 327.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 2-((4-Amino-6-methyl-5-oxo-4,5-dihydro-1,2,4-triazin-3-yl)thio)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide (CAS 508186-71-8)
- Ethyl 1-benzyl-4-(4-fluorophenyl)pyrrolidine-3-carboxylate (CAS 874990-58-6)
- Fmoc-L-allo-threoninol (CAS 252049-03-9)
- Citalopram Impurity 22 (CAS 227954-87-2)
- Methyl 4-(difluoromethyl)-5-hydroxy-2-methoxybenzoate (CAS 2385870-77-7)
- 2-(4-Fluorophenoxy)-4-methoxy-3-(1H-1,2,4-triazol-5-yl)pyridine (CAS 341966-67-4)
- 4-(Butan-2-yloxy)-3-chloroaniline (CAS 5493-77-6)
- Methyl 2-(isopropylamino)-4-(1h-1,2,4-triazol-1-yl)butanoate (CAS 1339881-73-0)
- 1-(3-Methoxyphenyl)cyclopropanecarbonitrile (CAS 74205-01-9)
- 1-tert-Butyl 2-chloromethyl (2S,4R)-4-(difluoromethoxy)pyrrolidine-1,2-dicarboxylate (CAS 2137062-11-2)
- N-Acetyl-DL-glutamic acid (CAS 5817-08-3)
- Norcodeine O-Beta-D-Glucuronid (CAS 50444-03-6)
- (1S,4R)-1,2-Dimethyl-1,2,3,4-tetrahydroisoquinoline-4,7,8-triol (CAS 79201-27-7)
- Peptide 441 (CAS CATO-CPTD788441)
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