Betaxolol Impurity 15 CAS 87549-35-7
| CAS No. | 87549-35-7 |
| Molecular Formula | C18H29NO4 |
| Molecular Weight | 323.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Betaxolol Impurity 15 (CAS 87549-35-7, C18H29NO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C18H29NO4, Betaxolol Impurity 15 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 323.43 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H29NO4 |
| Molecular Weight | 323.43 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Nitrogen Atoms | 1 |
Related Betaxolol Standards
- Betaxolol-d5 (CAS 1189957-99-0)
- Betaxolol Impurity 21 (CAS CATO-C4X-155921)
- Betaxolol EP Impurity E (CAS 1329613-85-5)
- Betaxolol Impurity 11 (CAS CATO-C4X-155911)
- Betaxolol (CAS 63659-18-7)
- Betaxolol Impurity 14 (CAS CATO-C4X-155914)
- Betaxolol Impurity 20 (CAS CATO-C4X-155920)
- Betaxolol Impurity 16 (CAS CATO-C4X-155916)
Recommended Standards
- Propafenone Impurity 40 (CAS CATO-C4X-132240)
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- Evocalcet Impurity 17 (CAS 210367-24-1)
- Promethazine Impurity 27 (CAS 1209-66-1)
- Dexamethasone Impurity 102 (CAS CATO-C4X-1165102)
- Flibanserin Impurity 12 (CAS 16015-69-3)
- Sodium (R)-2,3-bis(heptadecanoyloxy)propyl hydrogen phosphate (CAS 154804-54-3)
- (3R)-3-(4-Fluoro-2-methylphenyl)piperazin-2-one (CAS 1153574-57-2)
- (3S)-3-ethynylpiperidine;hydrochloride (CAS 2199320-88-0)
- 3-Methyl-2-(5-(methylamino)-1,3,4-thiadiazol-2-yl)-7,8-dihydropyrrolo[1,2-a]thieno[2,3-d]pyrimidin-4(6H)-one (CAS 883276-11-7)
- 2-Iodoquinolin-4-ol (CAS 5652-12-0)
- 2-(8-Chloro-1,2,3,4-tetrahydroisoquinolin-4-yl)ethanol (CAS 885268-71-3)
- Semaglutide impurity 249 (CAS CATO-C4X-2226249)
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