Betaxolol EP Impurity E CAS 1329613-85-5
| CAS No. | 1329613-85-5 |
| Molecular Formula | C18H31NO3 |
| Molecular Weight | 309.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Betaxolol EP Impurity E is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 309.44 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Betaxolol EP Impurity E (CAS 1329613-85-5) is a certified pharmaceutical impurity reference standard with the molecular formula C18H31NO3 and a molecular weight of 309.44 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H31NO3 |
| Molecular Weight | 309.44 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 1 |
Related Betaxolol Standards
- Betaxolol Impurity 11 (CAS CATO-C4X-155911)
- Betaxolol (CAS 63659-18-7)
- Betaxolol-d5 (CAS 1189957-99-0)
- Betaxolol Impurity 15 (CAS 87549-35-7)
- Betaxolol Impurity 21 (CAS CATO-C4X-155921)
- Betaxolol Impurity 14 (CAS CATO-C4X-155914)
- Betaxolol Impurity 20 (CAS CATO-C4X-155920)
- Betaxolol Impurity 16 (CAS CATO-C4X-155916)
Recommended Standards
- 1-Isobutoxycarbonyl-2-isobutoxy-1,2-dihydroquinoline 2-isobutoxy-1-isobutoxycarbonyl-1,2-dihydroquinoline 38428-14-7 iidq isobutyl 1,2-dihydro-2-isobutoxy-1-quinoline-carboxylate isobutyl 1,2-dihydro-2-isobutoxy-1-quinolinecarboxylate (CAS 38428-14-7)
- Oseltamivir Impurity 125 (CAS CATO-C4X-1720125)
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- Cholesterol Impurity 36 (CAS 7199-91-9)
- 5-Bromo-2-cyclobutylpyrimidine (CAS 893567-22-1)
- 8-Hydroxy-1,2,3,4-tetrahydroisoquinoline Hydrobromide (CAS 110192-20-6)
- 2-(2-Chlorophenyl)succinic Acid (CAS 6954-40-1)
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- 1,2-Dihydropyrano[2,3-c]pyrazole-3,6-dione (CAS 104615-92-1)
- Des-Pro36-Tirzepatide (CAS CATO-CPTD788937)
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