5-Bromo-4-chloro-2-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine CAS 876343-79-2
| CAS No. | 876343-79-2 |
| Molecular Formula | C13H7BrClIN2O2S |
| Molecular Weight | 497.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 5-Bromo-4-chloro-2-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (CAS 876343-79-2), a certified reference material (molecular formula C13H7BrClIN2O2S, MW 497.53 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine/bromine/iodine substitution, 5-Bromo-4-chloro-2-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 497.53 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H7BrClIN2O2S |
| Molecular Weight | 497.53 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl/Br/I-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Bromo Standards
- 4-Bromo-6-chloro-2-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1227268-75-8)
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Recommended Standards
- 6-Amino-4-hydroxy-3-((4-(phenyldiazenyl)naphthalen-1-yl)diazenyl)naphthalene-2-sulfonic acid (CAS 224790-31-2)
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- 2-(1,3-Dioxoisoindolin-2-yl)-N-(4-((3-ethynylphenyl)amino)quinazolin-6-yl)ethanesulfonamide (CAS 183321-69-9)
- (3-(4-Chlorophenyl)-5,6-dihydropyridazin-1(4H)-yl)(cyclopropyl)methanone (CAS 478261-57-3)
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- 3-(Aminomethyl)-3-phenylcyclobutan-1-ol (CAS 1334488-50-4)
- Elagolix Impurity 95 (CAS CATO-C4X-206895)
- 7-(4-Fluorophenyl)-2-((3,4,4-trifluorobut-3-en-1-yl)thio)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 478043-72-0)
- tert-Butyl 2-(6-chloropyridin-3-yl)pyrrolidine-1-carboxylate (CAS 1352534-35-0)
- Insulin Degludec impurity 4 (CAS CATO-C4X-21574)
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