Ceftriaxone impurity 52 CAS 876500-90-2

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.876500-90-2
Molecular FormulaC7H5NOS2
Molecular Weight183.25 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Ceftriaxone impurity 52 CAS 876500-90-2 chemical structure

Description

Ceftriaxone impurity 52 (C7H5NOS2) contains an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, an aromatic ring system. Its physicochemical properties are representative of its class; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Ceftriaxone impurity 52 (CAS 876500-90-2) is a certified pharmaceutical impurity reference standard with the molecular formula C7H5NOS2 and a molecular weight of 183.25 g/mol.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC7H5NOS2
Molecular Weight183.25 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Nitrogen Atoms1
Sulfur Atoms2

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