5,6-Dimethoxy-2-methyl-8-nitro-1,2,3,4-tetrahydroisoquinoline CAS 87664-83-3
| CAS No. | 87664-83-3 |
| Molecular Formula | C12H16N2O4 |
| Molecular Weight | 252.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5,6-Dimethoxy-2-methyl-8-nitro-1,2,3,4-tetrahydroisoquinoline is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5,6-Dimethoxy-2-methyl-8-nitro-1,2,3,4-tetrahydroisoquinoline (CAS 87664-83-3), molecular formula C12H16N2O4 and molecular weight 252.27 g/mol, is a CATO reference standard with documented purity and traceability.
5,6-Dimethoxy-2-methyl-8-nitro-1,2,3,4-tetrahydroisoquinoline (C12H16N2O4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5,6-Dimethoxy-2-methyl-8-nitro-1,2,3,4-tetrahydroisoquinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H16N2O4 |
| Molecular Weight | 252.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Nitrogen Atoms | 2 |
Related Dimethoxy Standards
- 1-(2,5-Dimethoxy-phenyl)-2-(1,3-dioxolan-2-yl)-ethanone (CAS 108950-30-7)
- 1-(2,6-Dimethoxy-phenyl)-2-(1,3-dioxolan-2-yl)-ethanone (CAS 1263365-51-0)
- 1-(3,5-Dimethoxy-phenyl)-2-(1,3-dioxolan-2-yl)-ethanone (CAS 1263365-59-8)
- 1-(2,3-Dimethoxy-phenyl)-2-(1,3-dioxolan-2-yl)-ethanone (CAS 1263365-66-7)
- 1-(2,4-Dimethoxy-phenyl)-2-(1,3-dioxolan-2-yl)-ethanone (CAS 1263365-93-0)
- 1-(3,4-Dimethoxy-phenyl)-2-(1,3-dioxolan-2-yl)-ethanone (CAS 1263366-10-4)
- 6,7-Dimethoxy-2-(methylsulfanyl)-3,4-dihydroquinazolin-4-one (CAS 1527466-89-2)
- 2,3-Dimethoxy-5-methyl-6-(3-methylbut-2-en-1-yl)benzene-1,4-diol (CAS 52590-98-4)
Recommended Standards
- 5-(Furan-2-yl)-4-(m-tolyldiazenyl)-1H-pyrazole (CAS 338414-25-8)
- 5-[3-(Benzyloxy)phenyl]-2H-tetrazole (CAS 710980-14-6)
- 5-(Boc-amino)pyridine-2-carboxamidoxime (CAS 814262-95-8)
- 5-Acetyl-1-(4-methylpiperazin-1-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 320420-08-4)
- Methyl 7-chloro-8-fluoro-4-hydroxyquinoline-2-carboxylate (CAS 1150164-88-7)
- 1-(2-Bromo-3-fluorophenyl)-2,2,2-trifluoroethan-1-ol (CAS 1850248-08-6)
- 6-Bromo-3-(difluoromethyl)-5-iodopicolinaldehyde (CAS 1806909-08-9)
- 3-Iodo-5-methyl-1H-pyrrolo[3,2-b]pyridine (CAS 1000343-70-3)
- 4-ethoxy-1,1,1-trichloro-3-buten-2-one (CAS 83124-74-7)
- Perfluoro-3,6-dioxa-4-methyl-7-octene-1-sulfonic acid (CAS 29311-67-9)
- CAS 62961-57-3 (CAS 62961-57-3)
- (11aR)-1,10-bis(3,5-bis(trifluoromethyl)phenyl)-12-hydroxy-3,8-dimethyl-4,5,6,7-tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocine 12-oxide (CAS 2098225-20-6)
- Chlorphenamine Impurity 24 (CAS CATO-C4X-118824)
- Semaglutide Impurity 187 (CAS CATO-C4X-2226187)
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