Methyl 7-chloro-8-fluoro-4-hydroxyquinoline-2-carboxylate CAS 1150164-88-7
| CAS No. | 1150164-88-7 |
| Molecular Formula | C11H7ClFNO3 |
| Molecular Weight | 255.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Methyl 7-chloro-8-fluoro-4-hydroxyquinoline-2-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Methyl 7-chloro-8-fluoro-4-hydroxyquinoline-2-carboxylate (CAS 1150164-88-7) is a high-purity analytical reference standard with the molecular formula C11H7ClFNO3 and a molecular weight of 255.63 g/mol.
The molecular framework of Methyl 7-chloro-8-fluoro-4-hydroxyquinoline-2-carboxylate (C11H7ClFNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H7ClFNO3 |
| Molecular Weight | 255.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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- 1,5-Dichloro-2-fluoro-3-nitrobenzene (CAS 501644-37-7)
- [14-31]-Semaglutide (CAS CATO-C4X-2226262)
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