Siponimod Impurity 1 CAS 877131-21-0
| CAS No. | 877131-21-0 |
| Molecular Formula | C9H11BrO |
| Molecular Weight | 215.09 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Siponimod Impurity 1 (C9H11BrO) contains a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 215.09 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a process- or degradation-related impurity, Siponimod Impurity 1 (CAS 877131-21-0, C9H11BrO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Siponimod Impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H11BrO |
| Molecular Weight | 215.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Br-containing |
Related Siponimod Standards
- Siponimod impurity 14 (CAS 2969211-32-1)
- Siponimod impurity 15 (CAS 2969312-21-6)
- Siponimod impurity 19 (CAS 2918890-06-7)
- Siponimod impurity 17 (CAS CATO-C4X-247217)
- Siponimod Impurity 9 (CAS 2746387-13-1)
- Siponimod Impurity 5 (CAS 957205-23-1)
- Siponimod Impurity 11 (CAS 2474774-17-7)
- Siponimod Impurity 8 (CAS CATO-C4X-24728)
Recommended Standards
- iotropium Bromide Impurity 12 (CAS 588-63-6)
- 4-(Bromomethyl)-2,6-dimethylphenol (CAS 45952-56-5)
- Anastrozole Impurity 29 (CAS CATO-C4X-123929)
- 3-Methoxy-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propan-1-amine (CAS 1073588-95-0)
- Telmisartan Impurity N2 (CAS 34981-09-4)
- Letermovir Impurity 87 (CAS CATO-C4X-291587)
- Roflumilast impurity 24 (CAS 1895-39-2)
- [(4-Fluorophenyl)methyl](propan-2-yl)amine (CAS 137379-61-4)
- N-(But-3-yn-2-yl)-4-methylbenzenesulfonamide (CAS 491879-61-9)
- 2-(2-Bromo-4,5-dimethoxyphenyl)ethan-1-amine hydrochloride (CAS 103275-23-6)
- 4-Methyl-3-nitro-N-(p-tolyl)benzenesulfonamide (CAS 295361-07-8)
- 2-Phenyl-3,4-dihydroisoquinolin-1(2H)-one (CAS 6772-51-6)
- 3-(4-Aminophenyl)-6-fluoro-7-(methylamino)quinazoline-2,4(1H,3H)-dione (CAS 936501-00-7)
- Angiotensin II Antipeptide (CAS 121379-63-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com