Conivaptan Impurity 4 CAS 877858-27-0

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.877858-27-0
Molecular FormulaC12H12N2O
Molecular Weight200.24 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Conivaptan Impurity 4 CAS 877858-27-0 chemical structure

Description

Conivaptan Impurity 4 (CAS 877858-27-0) is a certified pharmaceutical impurity reference standard with the molecular formula C12H12N2O and a molecular weight of 200.24 g/mol.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Conivaptan Impurity 4 is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 200.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Conivaptan Impurity 4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H12N2O
Molecular Weight200.24 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Nitrogen Atoms2

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