1-methyl-4-(trifluoromethyl)-1H-pyrazole-3-carboxylic acid CAS 878204-61-6
| CAS No. | 878204-61-6 |
| Molecular Formula | C6H9F3N2O2 |
| Molecular Weight | 198.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 1-methyl-4-(trifluoromethyl)-1H-pyrazole-3-carboxylic acid (CAS 878204-61-6), a certified reference material (molecular formula C6H9F3N2O2, MW 198.14 g/mol) for analytical method development and quality control.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, 1-methyl-4-(trifluoromethyl)-1H-pyrazole-3-carboxylic acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 198.14 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-methyl-4-(trifluoromethyl)-1H-pyrazole-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H9F3N2O2 |
| Molecular Weight | 198.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related methyl Standards
- 5-(trifluoromethyl)pyridazine-3-carboxylic acid (CAS 1211535-95-3)
- 3-(Trifluoromethyl)-1,8-naphthyridine (CAS 1261365-77-8)
- 2-[4-(trifluoromethyl)-1H-pyrazol-1-yl]acetic acid (CAS 1341347-35-0)
- 2-(Trifluoromethyl)quinoxaline (CAS 148853-42-3)
- 4-(Trifluoromethyl)tetrahydro-2H-pyran-4-carboxylic acid (CAS 1524761-14-5)
- 5-(Trifluoromethyl)quinazoline (CAS 16499-47-1)
- 6-(Trifluoromethyl)quinazoline (CAS 16499-48-2)
- 7-(Trifluoromethyl)quinazoline (CAS 16499-49-3)
Recommended Standards
- 1-[3-(trifluoromethyl)phenyl]prop-2-yn-1-one (CAS 72839-12-4)
- 2-(2,3,4-Trifluorophenyl)-1H-imidazole (CAS 438554-18-8)
- 1,1,1-Trifluoro-4-phenylbut-3-yn-2-one (CAS 58518-08-4)
- 2-(5-(Trifluoromethyl)tetrahydrofuran-2-yl)acetic acid (CAS 2126178-97-8)
- 4-Tolyl isothiocyanate p-tolylisothiocyanate 4-methylphenylisothiocyanate 1-isothiocyanato-4-methyl-benzene p-Tolyl isothiocyanate Isothiocyanic acid p-tolyl ester 4-Methylphenyl isothiocyanate 622-59-3 (CAS 622-59-3)
- 1-(2-Methylazetidin-1-yl)ethanone (CAS 50837-77-9)
- 7-Nitro-1,2,3,4-tetrahydrocyclopenta[b]indole (CAS 13687-72-4)
- Adenosine, 2'(or 3')-(dihydrogen phosphate) (CAS 82530-89-0)
- 4-Amino-1,2,3-benzothiadiazole (CAS 13599-80-9)
- N-(1-(Furan-2-carbonyl)indolin-6-yl)propane-2-sulfonamide (CAS 1040661-77-5)
- 7-Hydroxyimidazo[1,2-a]pyrimidin-5(1H)-one (CAS 1936552-46-3)
- Nalmefene Impurity 1 (CAS 42971-33-5)
- 2-((3-Cyano-6-(thiophen-2-yl)-4-(trifluoromethyl)pyridin-2-yl)thio)-N-(3,4-dimethoxyphenethyl)acetamide (CAS 496773-54-7)
- Q-Peptide trifluoroacetate salt (CAS 1361235-89-3)
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