Alverine EP Impurity E HCl CAS 878784-75-9
| CAS No. | 878784-75-9 |
| Molecular Formula | C27H33N |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Alverine EP Impurity E HCl (CAS 878784-75-9, C27H33NHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Alverine EP Impurity E HCl (C27H33NHCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C27H33N HCl |
| Molecular Weight | 408.03 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Alverine Standards
- Alverine EP Impurity A (CAS 104-52-9)
- Alverine Impurity 7 HCl (CAS 1199-99-1(free base))
- Alverine-D5 Citrate (CAS 1215327-00-6)
- Alverine EP Impurity B (CAS 122-97-4)
- Alverine EP Impurity C (CAS 13125-62-7)
- Alverine EP Impurity C HCl (CAS 13125-63-8)
- Alverine (CAS 150-59-4)
- Alverine EP Impurity D (CAS 2732347-30-5)
Recommended Standards
- Lidocaine Impurity 69 (CAS CATO-C4X-167969)
- Vericiguat Impurity 16 (CAS CATO-C4X-289616)
- Empagliflozin Impurity 58 (CAS 1620758-27-1)
- (2R,3R,4R,5R)-5-acetamido-2-(acetoxymethyl)-6-chlorotetrahydro-2H-pyran-3,4-diyl diacetate (CAS 109581-83-1)
- 2-(Aminomethyl)-5-(difluoromethyl)-6-methoxypyridine-3-carboxaldehyde (CAS 1361772-16-8)
- 6-Chloroquinolin-3-ol (CAS 860232-96-8)
- N'-Phenylbenzimidohydrazide hydrochloride (CAS 33244-00-7)
- 8-Hydroxy-7-iodoquinoline-6-sulfonic acid (CAS 292644-23-6)
- 6-Chloro-1-iodonaphthalene (CAS 1261868-37-4)
- 3X Flag Peptide trifluoroacetate salt (CAS 402750-12-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com