1,2,3,4,5-pentafluoro-6-nitrobenzene 2,3,4,5,6-Pentafluoronitrobenzene 880-78-4 CAS 880-78-4
| CAS No. | 880-78-4 |
| Molecular Formula | C6H6F5NO2 |
| Molecular Weight | 219.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1,2,3,4,5-pentafluoro-6-nitrobenzene 2,3,4,5,6-Pentafluoronitrobenzene 880-78-4 (C6H6F5NO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 1,2,3,4,5-pentafluoro-6-nitrobenzene 2,3,4,5,6-Pentafluoronitrobenzene 880-78-4 (CAS 880-78-4), a certified reference material (molecular formula C6H6F5NO2, MW 219.11 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H6F5NO2 |
| Molecular Weight | 219.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related pentafluoro Standards
- 2-(Pentafluoro-lambda6-sulfanyl)aniline (CAS 1246998-10-6)
- 5,5,6,6,6-Pentafluoro-2,2-dimethylhexan-3-one (CAS 177264-69-6)
- 2-(Pentafluoro-lambda6-sulfanyl)phenol (CAS 1126968-75-9)
- 5-(Pentafluoro-l6-sulfaneyl)pyridin-2-amine (CAS 1982380-97-1)
- 6-Oxo-2-(pentafluoro-λ6-sulfanyl)cyclohexa-2,4-dien-1-ylium (CAS 672-31-1)
- 2,2,3,3,3-Pentafluoro-1-(furan-2-yl)propan-1-ol (CAS 722491-60-3)
- 2,2,3,3,3-Pentafluoro-1-(furan-3-yl)propan-1-ol (CAS 722491-61-4)
- 3,3,4,4,4-Pentafluoro-2-hydroxy-2-methylbutyric acid methyl ester (CAS 723294-73-3)
Recommended Standards
- Butoconazole Impurity 1 (CAS 59363-13-2)
- 3-bromo-6-methyl-1H-pyrrolo[2,3-b]pyridine (CAS 1000340-28-2)
- 4-(2,5-Dichlorophenyl)butan-1-ol (CAS 854462-64-9)
- 3-bromo-5-methyl-1H-pyrrolo[3,2-b]pyridine (CAS 1000343-73-6)
- 4-((3-Methyl-4-nitrophenoxy)methyl)benzohydrazide (CAS 861237-97-0)
- 4-(cyclopropylmethoxy)-2,3-dihydro-1H-inden-1-ol (CAS 1340382-22-0)
- 1,2-Dibromo-4-chloro-3-fluorobenzene (CAS 1349708-99-1)
- 2-(5-Thiophen-2-yl-isoxazol-3-yl)-azepane (CAS 947015-78-3)
- Ethyl (5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)carbamate (CAS 116236-32-9)
- 3,8-Dimethylquinolin-2-amine hydrochloride (CAS 1170807-70-1)
- 1-(4-Isopropylphenyl)-N-methylmethanamine (CAS 73441-51-7)
- Lenalidomide Impurity 14 (CAS 18583-89-6)
- 6-Bromo-7-chloro-1,2,3,4-tetrahydroquinoline, 97% (CAS 1368146-30-8)
- Tirzepatide Impurity 13 (CAS CATO-C4X-324013)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com