1,4-Phenylenebis(phosphonic acid) CAS 880-68-2
| CAS No. | 880-68-2 |
| Molecular Formula | C6H8O6P2 |
| Molecular Weight | 238.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1,4-Phenylenebis(phosphonic acid) is closely related to a carbohydrate-derived structure, a phosphate ester group in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 1,4-Phenylenebis(phosphonic acid) (CAS 880-68-2), a certified reference material (molecular formula C6H8O6P2, MW 238.07 g/mol) for analytical method development and quality control.
The molecular framework of 1,4-Phenylenebis(phosphonic acid) (C6H8O6P2) is characterized by a carbohydrate-derived structure, a phosphate ester group. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1,4-Phenylenebis(phosphonic acid) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H8O6P2 |
| Molecular Weight | 238.07 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
Related Phenylenebis Standards
- 1,2-Phenylenebis(phosphonic acid) (CAS 28255-47-2)
- 1,3-Phenylenebis(phosphonic acid) (CAS 78271-46-2)
- 1,3-Phenylenebis((2-methylaziridin-1-yl)methanone) (CAS 7652-64-4)
- 2,2'-(1,4-Phenylenebis(methaneylylidene))dimalononitrile (CAS 17239-69-9)
- 1,4-Phenylenebis(dimethylsilanol) (CAS 2754-32-7)
- 1,4-Phenylenebis(thiourea) (CAS 1519-70-6)
- 2,2-(1,2-Phenylenebis(oxy))diacetic acid (CAS 5411-14-3)
- 2,2'-(1,4-Phenylenebis(oxy))diacetic acid (CAS 2245-53-6)
Recommended Standards
- 1,4-Dichloroimidazo[1,2-a]quinoxaline (CAS 2089314-93-0)
- 2-(((3,5-Dichlorophenyl)amino)methylene)malononitrile (CAS 42265-25-8)
- 1,4-Dichloro-5H-pyridazino[4,5-b]indole (CAS 80985-56-4)
- 2-(3-iodo-1-bicyclo[1.1.1]pentanyl)ethanol (CAS 2242693-92-9)
- O-Acetyl-3-(acetyloxy)-N-Boc-L-tyrosine (CAS 37402-63-4)
- 3-((4-Cyclohexylphenyl)amino)-1-phenyl-1H-pyrazol-5(4H)-one (CAS 22123-83-7)
- Methyl 4-Tosyl Mycophenoate-6-methyl-d (CAS 1185240-84-9)
- 1-Cyclopropyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine (CAS 2304631-68-1)
- Fmoc-(Dmb)Gly-OH (CAS 166881-42-1)
- 4-(2-Hydroxyethyl)-5-methyl-1-((2-nitrophenyl)sulfonyl)-2-phenyl-1,2-dihydro-3H-pyrazol-3-one (CAS 866039-77-2)
- 5-Methanesulfinylpentanenitrile (CAS 61121-66-2)
- (S)-2-Amino-2-methylpent-4-en-1-ol (CAS 1021869-87-3)
- Sodium 5-((2-(3-((methylthio)sulfonyl)propanamido)ethyl)amino)naphthalene-1-sulfonate (CAS 359436-83-2)
- Semaglutide impurity 197 (CAS CATO-C4X-2226197)
Why CATO?
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