1-{[2-(2,4-dimethylphenyl)-2-oxoethyl]sulfanyl}-4-[(2-methoxyphenyl)methyl]-4H,5H-[1,2,4]triazolo[4,3-a]quinazolin-5-one CAS 880279-88-9
| CAS No. | 880279-88-9 |
| Molecular Formula | C27H24N4O3S |
| Molecular Weight | 484.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 1-{[2-(2,4-dimethylphenyl)-2-oxoethyl]sulfanyl}-4-[(2-methoxyphenyl)methyl]-4H,5H-[1,2,4]triazolo[4,3-a]quinazolin-5-one (C27H24N4O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 18.0, corresponding to approximately 18 ring(s) or double-bond equivalent(s). With a molecular weight of 484.57 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 1-{[2-(2,4-dimethylphenyl)-2-oxoethyl]sulfanyl}-4-[(2-methoxyphenyl)methyl]-4H,5H-[1,2,4]triazolo[4,3-a]quinazolin-5-one (CAS 880279-88-9), a certified reference material (molecular formula C27H24N4O3S, MW 484.57 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-{[2-(2,4-dimethylphenyl)-2-oxoethyl]sulfanyl}-4-[(2-methoxyphenyl)methyl]-4H,5H-[1,2,4]triazolo[4,3-a]quinazolin-5-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H24N4O3S |
| Molecular Weight | 484.57 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related dimethylphenyl Standards
- 1-(3,5-Dimethylphenyl)-3-(5-phenyl-1-(2,4,6-trichlorophenyl)-1H-pyrazol-4-yl)urea (CAS 477713-90-9)
- N-(3,4-Dimethylphenyl)-N-(4-((2-oxo-5-(pyrrolidin-1-ylsulfonyl)pyridin-1(2H)-yl)methyl)thiazol-2-yl)acetamide (CAS 852828-79-6)
- N-(3,4-Dimethylphenyl)-1-methyl-3-(trifluoromethyl)-5-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)-1H-pyrazole-4-carboxamide (CAS 321553-25-7)
- 2-(2,5-Dimethylphenyl)-2-oxoethyl 6-bromo-2-(p-tolyl)quinoline-4-carboxylate (CAS 355421-84-0)
- 2-(3,4-Dimethylphenyl)-2-oxoethyl 6-bromo-2-(p-tolyl)quinoline-4-carboxylate (CAS 355421-81-7)
- 2-{4-[3-(3,4-dimethylphenyl)-1,2,4-oxadiazol-5-yl]-1-oxo-1,2-dihydrophthalazin-2-yl}-N-(4-ethylphenyl)acetamide (CAS 1708251-27-7)
- N-(2,6-dimethylphenyl)-2-((4-ethyl-5-(((6-oxo-1-phenyl-1,6-dihydropyridazin-3-yl)oxy)methyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 692737-11-4)
- 2-{[(2,5-dimethylphenyl)methyl]sulfanyl}-6,7-dimethoxy-3-[(4-methoxyphenyl)methyl]-3,4-dihydroquinazolin-4-imine (CAS 439096-24-9)
Recommended Standards
- (4S,4'S)-2,2'-((Phenylphosphinediyl)bis(2,1-phenylene))bis(4-isopropyl-4,5-dihydrooxazole) (CAS 186964-12-5)
- 2-(3-((2-((3-Acetamidophenyl)amino)-2-oxoethyl)sulfonyl)-1H-indol-1-yl)-N,N-diethylacetamide (CAS 878056-95-2)
- Lobeglitazone-d4 (CAS CATO-CCAD304334)
- Glisindamide (CAS 71010-45-2)
- α-Cortol (CAS 516-38-1)
- Methyl 3-(2-methoxyethoxy)propanoate (CAS 1092299-69-8)
- Mazindol-d4 (1.0mg/ml in Acetonitrile) (CAS 1246815-50-8)
- (2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)(pyridin-2-yl)methanone (CAS 1443331-23-4)
- Dimethyl 3-Hydroxyglutarate (CAS 7250-55-7)
- 1-Cyclopropylazetidine-2-methanol (CAS 1784914-12-0)
- 3-(2-Methyl-1H-imidazol-1-yl)benzaldehyde (CAS 1339213-76-1)
- Palbociclib Impurity 167 (CAS CATO-C4X-1125167)
- (2S,4R)-benzyl 4-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate 95687-41-5 A11166 Trans-N-benzyloxycarbonyl-4-hydroxy-2-hydroxymethylpyrrolidine (CAS 95687-41-5)
- D-[Phe6]-Semaglutide (CAS CATO-C4X-2226213)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com