4-Fluoro-1H-pyrazole-3-carboxylic acid CAS 881668-91-3

Purity 97%+In StockPharmaceutical Standards
CAS No.881668-91-3
Molecular FormulaC4H3FN2O2
Molecular Weight130.08 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Fluoro-1H-pyrazole-3-carboxylic acid CAS 881668-91-3 chemical structure

Description

The occurrence of 4-Fluoro-1H-pyrazole-3-carboxylic acid is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 4-Fluoro-1H-pyrazole-3-carboxylic acid (CAS 881668-91-3), a certified reference material (molecular formula C4H3FN2O2, MW 130.08 g/mol) for analytical method development and quality control.

4-Fluoro-1H-pyrazole-3-carboxylic acid (C4H3FN2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC4H3FN2O2
Molecular Weight130.08 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1987
Halogen ContentF-containing
Nitrogen Atoms2

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