6-Fluoropyrimidine-2,4(1H,3H)-dione CAS 591-36-6
| CAS No. | 591-36-6 |
| Molecular Formula | C4H3FN2O2 |
| Molecular Weight | 130.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Fluoropyrimidine-2,4(1H,3H)-dione.
6-Fluoropyrimidine-2,4(1H,3H)-dione (CAS 591-36-6), molecular formula C4H3FN2O2 and molecular weight 130.08 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 6-Fluoropyrimidine-2,4(1H,3H)-dione (C4H3FN2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 130.08 g/mol, it falls into the low-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-Fluoropyrimidine-2,4(1H,3H)-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C4H3FN2O2 |
| Molecular Weight | 130.08 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoropyrimidine Standards
- 5-Fluoropyrimidine-4,6-diol (CAS 106615-61-6)
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- 4-Ethyl-5-fluoropyrimidine-d3 (CAS 1794786-17-6)
- 5-Fluoropyrimidine-2,4-diamine (CAS 155-11-3)
- 6-Fluoropyrimidine-2,4-diamine (CAS 696-83-3)
- 4-Fluoropyrimidine-5-methanol (CAS 1804387-91-4)
- 4-Fluoropyrimidine-2-methanol (CAS 1806542-06-2)
- 2-Fluoropyrimidine-5-carbaldehyde (CAS 1240041-64-8)
Recommended Standards
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