2-Chloro-5-fluoro-4-methylpyridine CAS 881891-83-4
| CAS No. | 881891-83-4 |
| Molecular Formula | C6H5ClFN |
| Molecular Weight | 145.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Chloro-5-fluoro-4-methylpyridine is closely related to a nitrile group, fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-Chloro-5-fluoro-4-methylpyridine (CAS 881891-83-4) is a high-purity analytical reference standard with the molecular formula C6H5ClFN and a molecular weight of 145.56 g/mol.
The molecular framework of 2-Chloro-5-fluoro-4-methylpyridine (C6H5ClFN) is characterized by a nitrile group, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Chloro-5-fluoro-4-methylpyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H5ClFN |
| Molecular Weight | 145.56 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-Chloro-6-(fluoromethyl)pyridine (CAS 1026279-55-9)
- 3-Chloro-2-fluoro-5-methylpyridine (CAS 1031929-23-3)
- 4-Chloro-3-fluoro-2-methylpyridine (CAS 1195251-01-4)
- 5-Chloro-3-fluoro-2-methylpyridine (CAS 1210868-68-0)
- 3-Chloro-6-fluoro-2-methylpyridine (CAS 1214342-64-9)
- 3-Chloro-2-fluoro-4-methylpyridine (CAS 1214377-89-5)
- 4-Chloro-2-fluoro-6-methylpyridine (CAS 1227509-42-3)
- 2-Chloro-4-fluoro-5-methylpyridine (CAS 1227574-24-4)
Recommended Standards
- 2-Chloro-5-fluoro-3-methylpyridine (CAS 38186-84-4)
- 2-Chloro-5-fluoroaniline (CAS 452-83-5)
- 2-Chloro-5-(Fluoromethyl)Pyridine (CAS 253686-24-7)
- 2-Chloro-6-fluoroaniline (CAS 363-51-9)
- 5,5'-Oxydiisophthalic acid (CAS 1817605-38-1)
- 3-Hydroxy-2-methoxy-6-(methoxymethyl)benzoic acid (CAS 115319-77-2)
- 5-Bromo-4-chlorothiophene-2-sulfonyl chloride (CAS 1307307-49-8)
- 3,7-dimethyl-5-oxo-5h-[1,3]thiazolo[3,2-a]pyrimidine-2-carboxylic acid (CAS 1017419-69-0)
- 6-(Tert-butoxycarbonyl)-2-(1H-pyrrol-1-yl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylic acid (CAS 1215764-56-9)
- (E)-N'-{7-[1-(2-fluorophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}-N,N-dimethylmethanimidamide (CAS 477865-53-5)
- tert-Butyl 2-amino-4-(1-methyl-1H-pyrazol-4-yl)thiophene-3-carboxylate (CAS 1556208-90-2)
- 4-Methoxy-2-methylbenzo[d]thiazole-5-carboxylic acid (CAS 457947-78-3)
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