2-Chloro-5-fluoroaniline CAS 452-83-5
| CAS No. | 452-83-5 |
| Molecular Formula | C6H5ClFN |
| Molecular Weight | 145.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 145.56 g/mol gives 2-Chloro-5-fluoroaniline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Chloro-5-fluoroaniline (CAS 452-83-5), molecular formula C6H5ClFN and molecular weight 145.56 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrile group, fluorine/chlorine substitution, an aromatic ring system, 2-Chloro-5-fluoroaniline is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 145.56 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Chloro-5-fluoroaniline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H5ClFN |
| Molecular Weight | 145.56 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-Chloro-6-(fluoromethyl)pyridine (CAS 1026279-55-9)
- 3-Chloro-2-fluoro-5-methylpyridine (CAS 1031929-23-3)
- 4-Chloro-3-fluoro-2-methylpyridine (CAS 1195251-01-4)
- 5-Chloro-3-fluoro-2-methylpyridine (CAS 1210868-68-0)
- 3-Chloro-6-fluoro-2-methylpyridine (CAS 1214342-64-9)
- 3-Chloro-2-fluoro-4-methylpyridine (CAS 1214377-89-5)
- 4-Chloro-2-fluoro-6-methylpyridine (CAS 1227509-42-3)
- 2-Chloro-4-fluoro-5-methylpyridine (CAS 1227574-24-4)
Recommended Standards
- 2-Chloro-5-fluoro-4-methylpyridine (CAS 881891-83-4)
- 2-Chloro-6-fluoroaniline (CAS 363-51-9)
- 2-Chloro-5-fluoro-3-methylpyridine (CAS 38186-84-4)
- 3-(Chloromethyl)-5-fluoropyridine (CAS 39891-37-7)
- Fenclozic Acid (CAS 17969-20-9)
- 4-((4-(3-Phenyl-1,2,4-oxadiazol-5-yl)-1H-imidazol-1-yl)methyl)aniline (CAS 1351399-06-8)
- (3,3-Dimethylbutan-2-yl)benzene (CAS 19262-20-5)
- 2-Bromo-4-(3-bromopropyl)-1-(difluoromethoxy)benzene (CAS 1803865-74-8)
- N-(4-(4-chlorophenyl)thiazol-2-yl)-2-(phenylthio)acetamide (CAS 338959-60-7)
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- 3,4-Dimethoxybenzenesulfonyl Chloride (CAS 23095-31-0)
- Tau Peptide (244-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 330456-24-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com