Isavuconazole Impurity 238 HCl CAS CATO-C4X-1236238
| CAS No. | CATO-C4X-1236238 |
| Molecular Formula | C10H15N3O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 245.71 g/mol gives Isavuconazole Impurity 238 HCl distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Isavuconazole Impurity 238 HCl (CAS CATO-C4X-1236238) is a certified pharmaceutical impurity reference standard with the molecular formula C10H15N3O2HCl and a molecular weight of 245.71 g/mol.
The molecular framework of Isavuconazole Impurity 238 HCl (C10H15N3O2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Isavuconazole Impurity 238 HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H15N3O2 HCl |
| Molecular Weight | 245.71 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Isavuconazole Standards
- Isavuconazole Impurity 221 (CAS 1062201-83-5)
- Isavuconazole HCl (CAS 1121545-23-0)
- Isavuconazole Impurity 24 (CAS 1176988-44-5)
- Isavuconazole Impurity 33 (CAS 1180002-01-0)
- Isavuconazole Impurity 60 (CAS 123-73-9)
- Isavuconazole Impurity 62 (CAS 1286730-05-9)
- Isavuconazole-d4 (CAS 1346598-58-0)
- Isavuconazole Impurity N15 (CAS 1443-80-7)
Recommended Standards
- Trimetazidine Impurity 28 (CAS CATO-C4X-180328)
- Dacomitinib Impurity 40 (CAS CATO-C4X-208640)
- Lornoxicam Impurity 79 (CAS 1629463-16-6)
- 2-(4-Aminophenyl)hexahydro-1H-isoindole-1,3(2H)-dione (CAS 953722-90-2)
- 3-Bromo-4-fluoro-N-methylaniline (CAS 1233521-11-3)
- 5-((1H-benzo[d]imidazol-1-yl)methyl)-4-amino-4H-1,2,4-triazole-3-thiol (CAS 791806-33-2)
- 4-Fluoro-3-methyl-1H-pyrazole (CAS 133915-74-9)
- 2-(4-Bromo-2-chlorophenoxy)acetic acid (CAS 77228-67-2)
- Faropenem Impurity 11 Disodium Salt (CAS 130609-10-8)
- MCH-Gene-Overprinted-Polypeptide-14 (rat) (H-4746.0500) (CAS 182917-44-8)
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