(E)-[(2-Chlorophenyl)methoxy]({1-[4-(trifluoromethyl)pyridin-2-yl]propylidene})amine CAS 882747-74-2

Purity 97%+In StockPharmaceutical Standards
CAS No.882747-74-2
Molecular FormulaC16H14ClF3N2O
Molecular Weight342.74 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(E)-[(2-Chlorophenyl)methoxy]({1-[4-(trifluoromethyl)pyridin-2-yl]propylidene})amine CAS 882747-74-2 chemical structure

Description

The molecular framework of (E)-[(2-Chlorophenyl)methoxy]({1-[4-(trifluoromethyl)pyridin-2-yl]propylidene})amine (C16H14ClF3N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

(E)-[(2-Chlorophenyl)methoxy]({1-[4-(trifluoromethyl)pyridin-2-yl]propylidene})amine (CAS 882747-74-2) is a high-purity analytical reference standard with the molecular formula C16H14ClF3N2O and a molecular weight of 342.74 g/mol.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC16H14ClF3N2O
Molecular Weight342.74 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF/Cl-containing
Nitrogen Atoms2

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