Beclomethasone-d5 CAS 1263143-48-1
| CAS No. | 1263143-48-1 |
| Molecular Formula | - |
| Molecular Weight | 413.95 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Beclomethasone-d5.
Beclomethasone-d5 (CAS 1263143-48-1) is a high-purity analytical reference standard with the molecular formula C22H24D5ClO5 and a molecular weight of 413.95 g/mol.
The molecular framework of Beclomethasone-d5 (C22H24D5ClO5) is characterized by deuterium isotope labeling, a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Beclomethasone-d5 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H24D5ClO5 |
| Molecular Weight | 413.95 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
Related Beclomethasone Standards
- Beclomethasone (CAS CATO-C4X-147422)
- Beclomethasone (CAS 4419-39-0)
- Beclomethasone dipropionate Impurity 40 (CAS CATO-C4X-147440)
- Beclomethasone dipropionate Impurity 23 (CAS CATO-C4X-147423)
- Beclomethasone dipropionate Impurity 41 (CAS CATO-C4X-147441)
- Beclomethasone-Δ17,20 21-Aldehyde(E/Z Mixture) (CAS 1174035-77-8&1174035-80-3)
- Beclomethasone dipropionate Impurity 29 (CAS CATO-C4X-147429)
- Beclomethasone-17-Monopropionate-d3 (CAS CATO-C4X-147426)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com