6-Amino-4-(5-bromo-2-hydroxyphenyl)-3-(naphthalen-1-yl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile CAS 882750-21-2
| CAS No. | 882750-21-2 |
| Molecular Formula | C23H15BrN4O2 |
| Molecular Weight | 459.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Amino-4-(5-bromo-2-hydroxyphenyl)-3-(naphthalen-1-yl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile (CAS 882750-21-2), molecular formula C23H15BrN4O2 and molecular weight 459.29 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-Amino-4-(5-bromo-2-hydroxyphenyl)-3-(naphthalen-1-yl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile (C23H15BrN4O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H15BrN4O2 |
| Molecular Weight | 459.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 4 |
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Recommended Standards
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