2,2'-((4-Amino-6-chloropyrimidin-2-yl)azanediyl)diethanol CAS 88290-66-8
| CAS No. | 88290-66-8 |
| Molecular Formula | C8H13ClN4O2 |
| Molecular Weight | 232.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,2'-((4-Amino-6-chloropyrimidin-2-yl)azanediyl)diethanol (C8H13ClN4O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 2,2'-((4-Amino-6-chloropyrimidin-2-yl)azanediyl)diethanol (CAS 88290-66-8), a certified reference material (molecular formula C8H13ClN4O2, MW 232.67 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2,2'-((4-Amino-6-chloropyrimidin-2-yl)azanediyl)diethanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H13ClN4O2 |
| Molecular Weight | 232.67 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Amino Standards
- (2-Amino-5-chlorophenyl)(pyridin-4-yl)methanone (CAS 105192-42-5)
- 5-Amino-4-cyano-1-(3-chlorophenyl)-3-methylpyrazole (CAS 107842-57-9)
- 5-Amino-1-(2-chlorophenyl)-3-methyl-1H-pyrazole-4-carbonitrile (CAS 107856-31-5)
- 5-Amino-1-(5-chloro-2-methylphenyl)-1H-pyrazole-4-carbonitrile (CAS 1159678-51-9)
- 5-Amino-1-(2-chloro-6-methylphenyl)-1H-pyrazole-4-carbonitrile (CAS 1159678-59-7)
- (2-Amino-4-chloropyridin-3-yl)(phenyl)methanone (CAS 1203510-05-7)
- 5-Amino-1-(3-chloro-2-methylphenyl)-1H-pyrazole-4-carbonitrile (CAS 1207832-99-2)
- 2-(3-Amino-4-chloro-1h-pyrazol-1-yl)-n-(2-methoxyethyl)acetamide (CAS 1344066-59-6)
Recommended Standards
- 2-(4-Chlorophenyl)-6-oxo-1,4,5,6-tetrahydropyridine-3-carbonitrile (CAS 478081-46-8)
- 2,2'-((5-Amino-6-chloropyrimidin-4-yl)azanediyl)diethanol (CAS 88627-16-1)
- 2-((7-Chloro-2-methylquinolin-8-yl)oxy)acetonitrile (CAS 88757-69-1)
- 2-Chloro-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-4-one (CAS 75536-00-4)
- Azidomethylcyclopentane (CAS 455256-35-6)
- rac-1,2-Dilinolenoyl-3-chloropropanediol (CAS 74875-97-1)
- 1220019-22-6 N-Benzyl-N-(2-piperidinylmethyl)-1-ethanaminedihydrochloride (CAS 1220019-22-6)
- Tenofovir Impurity 68 (CAS 1643116-24-8)
- Ethyl 1-(4-methylbenzyl)-4-(phenylsulfonyl)piperidine-4-carboxylate (CAS 860649-16-7)
- 7-(1,3-Dioxaindan-5-yl)-1-methyl-2,4-dioxo-1h,2h,3h,4h-pyrido[2,3-d]pyrimidine-5-carboxylic acid (CAS 879303-83-0)
- n-(3-Aminophenyl)azepane-1-carboxamide (CAS 1040012-46-1)
- Isavuconazole Impurity 71 (CAS CATO-C4X-123671)
- 4-(4-Methoxyphenyl)picolinaldehyde (CAS 1287217-25-7)
- Semaglutide impurity 227 (CAS CATO-C4X-2226227)
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