Cefuroxime Impurity 35 CAS 883-40-9
| CAS No. | 883-40-9 |
| Molecular Formula | C13H10N2 |
| Molecular Weight | 194.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Cefuroxime Impurity 35.
As a process- or degradation-related impurity, Cefuroxime Impurity 35 (CAS 883-40-9, C13H10N2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Cefuroxime Impurity 35 (C13H10N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Cefuroxime Impurity 35 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H10N2 |
| Molecular Weight | 194.23 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
Related Cefuroxime Standards
- Cefuroxime Impurity 58 (CAS 54434-94-5)
- Cefuroxime Axetil Impurity 7 (CAS 59176-08-8)
- Cefuroxime Impurity 41 (CAS CATO-C4X-124541)
- Cefuroxime Impurity 82 (CAS CATO-C4X-124582)
- Cefuroxime Axetil Impurity 8 (CAS 26395-99-3)
- Cefuroxime Impurity 93 (CAS CATO-C4X-124593)
- Cefuroxime Sodium Impurity 14 (CAS 69384-96-9)
- Cefuroxime Sodium EP Impurity I (CAS 39684-61-2)
Recommended Standards
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- Bisoprolol Impurity 49 (CAS 104857-48-9)
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- Pregabalin EP Impurity D (CAS 89015-27-0)
- Eldecalcitol Impurity 32 (CAS 2106839-39-6)
- Bazedoxifene Acetate Impurity 13 (CAS CATO-C4X-128813)
- Difelikefalin Impurity 66 (CAS CATO-C4X-304166)
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