Cefuroxime Axetil Impurity 7 CAS 59176-08-8
| CAS No. | 59176-08-8 |
| Molecular Formula | C7H6ClNO3 |
| Molecular Weight | 187.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Cefuroxime Axetil Impurity 7 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Cefuroxime Axetil Impurity 7 (CAS 59176-08-8), a pharmacopoeial impurity reference standard (molecular formula C7H6ClNO3, MW 187.58 g/mol) used for the identification and quantification of trace impurities in APIs.
Cefuroxime Axetil Impurity 7 (C7H6ClNO3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C7H6ClNO3 |
| Molecular Weight | 187.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Cefuroxime Standards
- Cefuroxime Impurity 58 (CAS 54434-94-5)
- Cefuroxime Impurity 41 (CAS CATO-C4X-124541)
- Cefuroxime Impurity 35 (CAS 883-40-9)
- Cefuroxime Sodium Impurity 14 (CAS 69384-96-9)
- Cefuroxime Sodium EP Impurity I (CAS 39684-61-2)
- Cefuroxime Impurity 82 (CAS CATO-C4X-124582)
- Cefuroxime Axetil Impurity 8 (CAS 26395-99-3)
- Cefuroxime Impurity 93 (CAS CATO-C4X-124593)
Recommended Standards
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- Ifosfamide EP Impurity A (CAS 22608-58-8)
- Ketorolac Impurity 26 (CAS 111930-01-9)
- Ixazomib Impurity 7 (CAS CATO-C4X-12677)
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- 3-[(E)-2-(Furan-2-yl)ethenyl]-1-(4-methylphenyl)urea (CAS 1164560-43-3)
- 5-bromobenzofuro[2,3-b]pyridine (CAS 2722775-02-0)
- 4-(3-Cyanopropoxy)-benzamide (CAS 125439-52-3)
- Semaglutide impurity 74 (CAS CATO-C4X-222674)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com