3,7-Dichloroquinoline-8-carbonitrile CAS 88347-01-7

Purity 97%+In StockPharmaceutical Standards
CAS No.88347-01-7
Molecular FormulaC10H4Cl2N2
Molecular Weight223.06 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3,7-Dichloroquinoline-8-carbonitrile CAS 88347-01-7 chemical structure

Description

The occurrence of 3,7-Dichloroquinoline-8-carbonitrile is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

3,7-Dichloroquinoline-8-carbonitrile (CAS 88347-01-7) is a high-purity analytical reference standard with the molecular formula C10H4Cl2N2 and a molecular weight of 223.06 g/mol.

3,7-Dichloroquinoline-8-carbonitrile (C10H4Cl2N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3,7-Dichloroquinoline-8-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H4Cl2N2
Molecular Weight223.06 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1982
Halogen ContentCl-containing
Nitrogen Atoms2

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