Loxoprofen Impurity 131 CAS CATO-C4X-1488131
| CAS No. | CATO-C4X-1488131 |
| Molecular Formula | C16H22O3 |
| Molecular Weight | 262.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Loxoprofen Impurity 131 (C16H22O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 262.34 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Loxoprofen Impurity 131 (CAS CATO-C4X-1488131, C16H22O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Loxoprofen Impurity 131 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H22O3 |
| Molecular Weight | 262.34 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Loxoprofen Standards
- Loxoprofen Impurity 146 (CAS CATO-C4X-1488146)
- Loxoprofen Impurity 15(Mixture of Diastereomers) (CAS 1091621-62-3)
- Loxoprofen Impurity 82 (CAS CATO-C4X-148882)
- Loxoprofen impurity 94 (CAS CATO-C4X-148894)
- Loxoprofen impurity 95 (CAS CATO-C4X-148895)
- Loxoprofen Impurity 160 (CAS CATO-C4X-1488160)
- Loxoprofen Dihydroxy Impurity (CAS 88378-22-7)
- Loxoprofen Impurity 11 (CAS 81762-92-7)
Recommended Standards
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- Siponimod Impurity 8 (CAS CATO-C4X-24728)
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- Decitabine Impurity 24 (CAS 1207459-15-1)
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- Camphor EP Impurity H (CAS CATO-C4X-211413)
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- 2-((4-Ethyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(4-methoxyphenyl)acetamide (CAS 433235-42-8)
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