1-(4-Fluorophenyl)-4-(1-(2-phenoxyethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one CAS 883648-91-7
| CAS No. | 883648-91-7 |
| Molecular Formula | C25H22FN3O2 |
| Molecular Weight | 415.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(4-Fluorophenyl)-4-(1-(2-phenoxyethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 1-(4-Fluorophenyl)-4-(1-(2-phenoxyethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one (CAS 883648-91-7), a certified reference material (molecular formula C25H22FN3O2, MW 415.46 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 1-(4-Fluorophenyl)-4-(1-(2-phenoxyethyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 415.46 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H22FN3O2 |
| Molecular Weight | 415.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Fluorophenyl Standards
- (4-((4-Fluorophenyl)sulfonyl)piperazin-1-yl)(3-(trifluoromethyl)phenyl)methanone (CAS 866152-65-0)
- 1-((4-Fluorophenyl)sulfonyl)-N-(3-(trifluoromethyl)phenyl)pyrrolidine-2-carboxamide (CAS 317377-86-9)
- 2-{[(3-fluorophenyl)methyl]sulfanyl}-4-(4-methylphenyl)-1H,4H,5H-indeno[1,2-d]pyrimidin-5-one (CAS 691873-10-6)
- 4-(2-Fluorophenyl)-2-{[(4-methylphenyl)methyl]sulfanyl}-1H,4H,5H-indeno[1,2-d]pyrimidin-5-one (CAS 860788-33-6)
- 1-[(2-Fluorophenyl)methyl]-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea (CAS 1796898-53-7)
- 1-[(3-Fluorophenyl)methyl]-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea (CAS 1796915-83-7)
- 6-(4-((4-Fluorophenyl)sulfonyl)piperazin-1-yl)-N-(pyridin-4-yl)pyridazin-3-amine (CAS 1021039-28-0)
- 5-(2-Fluorophenyl)-3-hydroxy-1-(2-morpholinoethyl)-4-(thiophene-2-carbonyl)-1H-pyrrol-2(5H)-one (CAS 381188-66-5)
Recommended Standards
- (S)-2-(3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-1,1-dioxidotetrahydrothiophen-3-yl)acetic acid (CAS 2381096-41-7)
- 1-Amino-2,4-dibromo-7-chloroanthracene-9,10-dione (CAS 88605-95-2)
- (11bS)-N,N-Dipropyldinaphtho[2,1-d:1’,2’-f][1,3,2]dioxaphosphepin-4-amine (CAS 802902-36-9)
- 2-((5-(Benzo[d][1,3]dioxol-5-yl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-1-phenylethan-1-one (CAS 325694-50-6)
- 2-(((4H-1,2,4-triazol-4-yl)amino)methyl)-4-methylphenol (CAS 732256-62-1)
- 2-bromo-7-methoxy-3-methyl-9H-carbazole (CAS 2649492-68-0)
- 6-Isopropoxy-5-methylnicotinic acid (CAS 1011558-18-1)
- 4-Benzyl-5-methyl-1,3-thiazol-2-amine (CAS 91088-89-0)
- 5-Methyl-3-(4-phenylphenyl)-1,2-oxazole-4-carboxylic acid (CAS 55278-63-2)
- 1,3-Bis(1,5-dimethyl-1h-pyrazol-4-yl)propane-1,3-dione (CAS 1006343-72-1)
- Ethyl 3-(difluoromethyl)-1h-pyrazole-5-carboxylate (CAS 936033-53-3)
- 4-Amino-3-fluoro-2-methyl-2-butanol (CAS 1823408-55-4)
- Ethyl 5,5-difluoro-4,5,6,7-tetrahydro-1H-indazole-3-carboxylate (CAS 2282704-43-0)
- Insulin Lispro (CAS 133107-64-9)
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