Ziprasidone Impurity 12 CAS 884305-08-2
| CAS No. | 884305-08-2 |
| Molecular Formula | C21H21ClN4O2S |
| Molecular Weight | 428.94 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ziprasidone Impurity 12 is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Ziprasidone Impurity 12 (CAS 884305-08-2) is a certified pharmaceutical impurity reference standard with the molecular formula C21H21ClN4O2S and a molecular weight of 428.94 g/mol.
Based on its molecular formula C21H21ClN4O2S, Ziprasidone Impurity 12 contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 428.94 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H21ClN4O2S |
| Molecular Weight | 428.94 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Ziprasidone Standards
- Ziprasidone Impurity 11 (CAS 188797-76-4)
- Ziprasidone Impurity 30 (CAS 188797-80-0)
- Ziprasidone Impurity 59 (CAS CATO-C4X-124059)
- Ziprasidone EP Impurity C (CAS 1159977-64-6)
- Ziprasidone Impurity 24 (CAS 884305-07-1)
- Ziprasidone EP Impurity B (CAS 1159977-56-6)
- Ziprasidone-d8 (CAS 1126745-58-1)
- Ziprasidone Impurity 46 (CAS 2369664-19-5)
Recommended Standards
- 4-[3-(4-Chlorobenzenesulfonyl)-4-methyl-6-phenylpyridin-2-yl]morpholine (CAS 478262-72-5)
- (3-(((4-Chlorophenyl)sulfonyl)methyl)-4-(1H-pyrrol-1-yl)phenyl)(pyrrolidin-1-yl)methanone (CAS 339101-88-1)
- 2,2'-(4,6-Dichloro-5-methoxy-1,3-phenylene)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) (CAS 1221589-79-2)
- Capivasertib Impurity 1 (CAS 1143532-51-7)
- Norepinephrine Impurity 84 (CAS CATO-C4X-151484)
- Rivastigmine Impurity 19 (CAS CATO-C4X-138419)
- Ambroxol Sorbide Impurity 2(Ambroxol Impurity 78) (CAS CATO-C4X-108578)
- 1-(3-Amino-4-(benzyloxy)-2-hydroxyphenyl)ethan-1-one (CAS 871101-87-0)
- Methyl 4-((tert-butoxycarbonyl)amino)-2-iodobenzoate (CAS 1949842-89-0)
- 3-(2-chloro-6-methoxyphenyl)-5-methyl-1,2-oxazole-4-carboxylic acid (CAS 1364523-60-3)
- 1-Ethyl-6,8-difluoro-2-methylquinolin-4(1H)-one (CAS 1210975-11-3)
- 2-(2,5-Dimethoxyphenyl)-1,3-dioxoisoindoline-5-carboxylic acid (CAS 356574-17-9)
- Iron phosphide, Fe <SUB> 3 </SUB> P (CAS 12023-53-9)
- Myristoyl Pentapeptide-4 (CAS 1392416-25-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com