Ethyl 5-amino-2-chloronicotinate CAS 884495-40-3
| CAS No. | 884495-40-3 |
| Molecular Formula | C8H9ClN2O2 |
| Molecular Weight | 200.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Ethyl 5-amino-2-chloronicotinate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Ethyl 5-amino-2-chloronicotinate (CAS 884495-40-3) is a high-purity analytical reference standard with the molecular formula C8H9ClN2O2 and a molecular weight of 200.62 g/mol.
Based on its molecular formula C8H9ClN2O2, Ethyl 5-amino-2-chloronicotinate contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 200.62 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H9ClN2O2 |
| Molecular Weight | 200.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Ethyl Standards
- Methyl 3-amino-6-chloro-2-methylisonicotinate (CAS 1073182-63-4)
- Ethyl 3-amino-2-chloroisonicotinate (CAS 1093759-41-1)
- Ethyl 4-amino-2-chloronicotinate (CAS 1194341-67-7)
- Ethyl 5-amino-4-chloropicolinate (CAS 1196156-76-9)
- Ethyl 5-amino-6-chloropicolinate (CAS 1256819-09-6)
- (2S)-2-amino-3-(3-chloropyridin-2-yl)propanoic acid (CAS 1270287-91-6)
- Ethyl 3-amino-6-chloropyridine-2-carboxylate (CAS 1352200-86-2)
- methyl 3-amino-2-chloro-6-methylpyridine-4-carboxylate (CAS 1369085-33-5)
Recommended Standards
- Ethyl 5-amino-2-chloroisonicotinate (CAS 862314-10-1)
- Ethyl 5-amino-3-chloropicolinate (CAS 872355-65-2)
- Ethyl 4-chloro-2-methylpyrimidine-5-carboxylate (CAS 2134-36-3)
- Ethyl 5-amino-6-chloro-3-pyridinecarboxylate (CAS 390816-56-5)
- N-(bis(dibutylamino)methylene)-N-butylbutan-1-aminium chloride (CAS 89450-31-7)
- Ethyl 4-chloro-7-nitroquinoline-2-carboxylate (CAS 1447608-14-1)
- 3-iodo-5-nitro-pyridin-2-amine (CAS 25391-56-4)
- 2-Amino-3,5-dibromopyrazin-1-ium-1-olate (CAS 84539-09-3)
- 2-Amino-N-methyl-N-(1-methyl-piperidin-3-yl)-acetamide (CAS 1249956-38-4)
- N-(3-(Benzo[d]oxazol-2-yl)-4-hydroxy-5-methylphenyl)-5-nitrofuran-2-carboxamide (CAS 929812-41-9)
- Hydroxycitric Acid (CAS 6205-14-7)
- 2,4-Dichloro-N-(2-((2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)amino)phenyl)benzamide (CAS 338772-79-5)
- 1-Boc-4-(4-bromobenzoyl)piperidine (CAS 439811-37-7)
- Galanin Message Associated Peptide (44-59) amide (CAS 125455-59-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com