5-Fluoro-8-methylquinoline CAS 88474-18-4
| CAS No. | 88474-18-4 |
| Molecular Formula | C10H8FN |
| Molecular Weight | 161.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Fluoro-8-methylquinoline (C10H8FN) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
5-Fluoro-8-methylquinoline (CAS 88474-18-4) is a high-purity analytical reference standard with the molecular formula C10H8FN and a molecular weight of 161.18 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Fluoro-8-methylquinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8FN |
| Molecular Weight | 161.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 8-Fluoro-6-methylquinoline (CAS 1050910-73-0)
- 6-Fluoro-5-methylquinoline (CAS 107224-22-6)
- 7-Fluoro-2-methylquinoline (CAS 1128-74-1)
- 6-Fluoro-8-methylquinoline (CAS 1150271-14-9)
- 7-fluoro-6-methylisoquinoline (CAS 1159983-16-0)
- 4-Fluoro-2,3-dihydro-1H-indene-1-carbonitrile (CAS 1188174-13-1)
- 8-Fluoro-5-methylquinoline (CAS 1241746-03-1)
- 8-Fluoro-3-methylquinoline (CAS 1241746-05-3)
Recommended Standards
- 5-Fluoro-6-methylquinoline (CAS 503538-41-8)
- 5-nitrothiophene-3-carbaldehyde (CAS 75428-45-4)
- 5-Fluoro-2-methylquinoline (CAS 346604-38-4)
- 6-Fluoro-1-methylisoquinoline (CAS 608515-77-1)
- 2-(3-(Trifluoromethyl)-1H-pyrazol-4-yl)ethanol (CAS 185853-85-4)
- (1S,3S,4R)-ent-Entecavir (CAS 1367369-79-6)
- 1-(3-(4-Bromo-1H-pyrazol-1-yl)phenyl)ethanone (CAS 1517800-84-8)
- 1-(4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,1'-biphenyl]-4-yl)ethanone (CAS 269410-19-7)
- Dicamba-5-hydroxy-desmethyl (CAS 18688-01-2)
- 4-(Methylsulfinyl)-2-[(phenylsulfonyl)amino]butanoic acid (CAS 1008434-66-9)
- Methyl 3-(3,5-difluorophenyl)-5-methoxybenzoate (CAS 1820747-70-3)
- 1-(3-Chlorophenyl)-3-(o-tolyl)-1H-pyrazol-5-amine (CAS 618098-33-2)
- Lysine Impurity 20 (CAS 1946-82-3)
- Semaglutide impurity 58 (CAS CATO-C4X-222658)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com