5-Iodo-8-methylquinoline CAS 88474-17-3
| CAS No. | 88474-17-3 |
| Molecular Formula | C10H8IN |
| Molecular Weight | 269.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 269.08 g/mol gives 5-Iodo-8-methylquinoline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-Iodo-8-methylquinoline (CAS 88474-17-3), molecular formula C10H8IN and molecular weight 269.08 g/mol, is a CATO reference standard with documented purity and traceability.
5-Iodo-8-methylquinoline (C10H8IN) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, iodine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Iodo-8-methylquinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8IN |
| Molecular Weight | 269.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Iodo Standards
- 3-IODO-5-METHYLCINNAMONITRILE (CAS 1018450-07-1)
- 6-Iodo-2-methylquinoline (CAS 1128-62-7)
- 3-Iodo-2-methylquinoline (CAS 1207875-09-9)
- 8-Iodo-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine (CAS 1228666-17-8)
- 6-Iodo-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine (CAS 1246088-42-5)
- 2-Iodo-isonicotinic acid methyl ester (CAS 134579-47-8)
- 3-iodo-8-methylquinoline (CAS 1424245-96-4)
- 3-Iodo-6-methylquinoline (CAS 1424246-00-3)
Recommended Standards
- 5-Bromo-2,4-difluorobiphenyl (CAS 2230481-35-1)
- 5-Iodonaphthalen-1-amine (CAS 66640-75-3)
- 5-(N-Boc-Amino)-4-fluoro-2-methylphenylboronic acid (CAS 2377611-77-1)
- 6-(Iodomethyl)quinoline (CAS 99361-10-1)
- 3-(4-(2-((6-Amino-9-((2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxytetrahydro-furan-2-yl)-9H-purin-2-yl)amino)ethyl)phenyl)propanoic acid hydrochloride (CAS 120225-54-9)
- 3-Bromo-7-(trifluoromethyl)imidazo[1,2-a]pyrimidine (CAS 375857-65-1)
- 6-(Chloromethyl)benzo[de]isochromen-1(3H)-one (CAS 1018-47-9)
- Nicotinamide EP Impurity C (CAS 1452-77-3)
- 2-Phenyl-2-[(2-thienylcarbonyl)amino]ethyl 2-thiophenecarboxylate (CAS 338750-52-0)
- 1,1-Difluoro-4-methylcyclohexane (CAS 74185-74-3)
- ethyl 5-oxo-5H,6H,7H-cyclopenta[b]pyridine-6-carboxylate (CAS 1609572-20-4)
- (2,4-Difluorophenyl)(piperazin-1-yl)methanone hydrochloride (CAS 1065586-37-9)
- 1,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyridazine (CAS 91846-80-9)
- Semaglutide impurity 86 (CAS CATO-C4X-152686)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com