Olmesartan Impurity 45 CAS 885216-74-0
| CAS No. | 885216-74-0 |
| Molecular Formula | C33H25ClN4 |
| Molecular Weight | 513.03 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, Olmesartan Impurity 45 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 513.03 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Olmesartan Impurity 45 (CAS 885216-74-0) is a certified pharmaceutical impurity reference standard with the molecular formula C33H25ClN4 and a molecular weight of 513.03 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Olmesartan Impurity 45 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C33H25ClN4 |
| Molecular Weight | 513.03 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 23.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Olmesartan Standards
- Olmesartan Impurity 108 (CAS CATO-C4X-1097108)
- Olmesartan Impurity 46 (CAS 155983-56-5)
- Olmesartan impurity 99 (CAS 1427168-36-2)
- Olmesartan Impurity 116 (CAS 3092204-98-0)
- Olmesartan Medoxomil EP Impurity C (CAS 879562-26-2)
- Olmesartan impurity C (CAS CATO-C4X-10973)
- Olmesartan Impurity 55 (CAS 1227626-44-9)
- Olmesartan Impurity 56 (CAS 2347585-74-2)
Recommended Standards
- 4-(((5'-chloro-2'-(((1R,4r)-4-(((R)-1-methoxypropan-2-yl)amino)cyclohexyl)amino)-[2,4'-bipyridin]-6-yl)amino)methyl)tetrahydro-2H-pyran-4-carbonitrile (CAS 1263373-43-8)
- Talmapimod (CAS 309913-83-5)
- 2-((4-Chloro-6-((4-(naphthalen-2-yl)thiazol-2-yl)amino)pyrimidin-2-yl)thio)octanoic acid (CAS 1492060-44-2)
- PUMECITINIB Impurity 2 (CAS CATO-C4X-35662)
- Tryptophan Impurity 15 (CAS CATO-C4X-137315)
- Olmesartan Impurity 34 (CAS 116857-04-6)
- Hydrochlorothiazide Impurity 7 (CAS CATO-C4X-11777)
- 6-Bromo-2-cyano-3-(trifluoromethyl)benzenesulfonyl chloride (CAS 1805499-64-2)
- 2-Iodo-4,5-dimethylpyridine (CAS 512197-94-3)
- 1-(1H-Pyrrolo[3,2-b]pyridin-5-yl)ethanone (CAS 1445856-03-0)
- 6-Methylpyridazine-3,4-dicarboxamide (CAS 16082-04-5)
- 934183-50-3 Fmoc-Met-OH-15N L-Methionine-15N, N-Fmoc N-(9-Fluorenylmethoxycarbonyl)-L-methionine-15N (CAS 934183-50-3)
- 2-({1-[(tert-butoxy)carbonyl]piperidin-4-yl}methyl)benzoic acid (CAS 910442-78-3)
- D-[Arg]30-Semaglutide (CAS CATO-C4X-222653)
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