3-(5-Chloro-2-(difluoromethoxy)phenyl)acrylic acid CAS 885456-96-2
| CAS No. | 885456-96-2 |
| Molecular Formula | C10H7ClF2O3 |
| Molecular Weight | 248.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 3-(5-Chloro-2-(difluoromethoxy)phenyl)acrylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies 3-(5-Chloro-2-(difluoromethoxy)phenyl)acrylic acid (CAS 885456-96-2), a certified reference material (molecular formula C10H7ClF2O3, MW 248.61 g/mol) for analytical method development and quality control.
The molecular framework of 3-(5-Chloro-2-(difluoromethoxy)phenyl)acrylic acid (C10H7ClF2O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7ClF2O3 |
| Molecular Weight | 248.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- Ethyl 2-(4-chloro-3,5-difluorophenyl)-2-oxoacetate (CAS 1256470-45-7)
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- 4-(2-Chloro-4,5-difluorophenyl)-4-oxobutyric acid (CAS 951891-43-3)
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Recommended Standards
- 1-Methyl-3-(trifluoromethyl)-1h-pyrazole-5-sulfonyl chloride (CAS 884340-52-7)
- 1-Methyl-3-(trifluoromethyl)-1h-pyrazole-4-sulfonyl chloride (CAS 519056-67-8)
- 1-methyl-5-(trifluoromethyl)-1H-pyrazole-4-sulfonyl chloride (CAS 1365939-85-0)
- 5-Methyl-2-(trifluoromethyl)furan-3-sulfonyl chloride (CAS 306935-02-4)
- (1R,2S)-2-Fluorocyclohexanamine hydrochloride (CAS 2059908-57-3)
- 5-(4-Bromophenyl)-5-phenylimidazolidine-2,4-dione (CAS 56079-85-7)
- 4-Iodo-3-methylbenzonitrile (CAS 42872-85-5)
- 2-Amino-7-methoxyquinoline-3-carboxylic acid (CAS 1780503-79-8)
- H-D-Asp(OBzl)-OBzl.HCl (CAS 5191-80-0)
- Pravastatin (CAS 81093-37-0)
- Tert-butyl 3-(trifluoromethoxy)piperidine-1-carboxylate (CAS 1206524-11-9)
- 2-(((6-(4-Methoxyphenyl)pyridazin-3-yl)thio)methyl)imidazo[1,2-a]pyridine (CAS 1207038-45-6)
- 7-Chloro-1-cyclopropyl-1,4-dihydro-8-methyl-4-oxo-3-quinolinecarboxylic Acid (CAS 103877-20-9)
- Vasonatrin Peptide (VNP) trifluoroacetate salt (CAS 141676-35-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com