3-(3,5-Bis(trifluoromethyl)phenoxy)benzenesulfonyl chloride CAS 885950-87-8
| CAS No. | 885950-87-8 |
| Molecular Formula | C14H7ClF6O3S |
| Molecular Weight | 404.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 404.71 g/mol gives 3-(3,5-Bis(trifluoromethyl)phenoxy)benzenesulfonyl chloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-(3,5-Bis(trifluoromethyl)phenoxy)benzenesulfonyl chloride (CAS 885950-87-8) is a high-purity analytical reference standard with the molecular formula C14H7ClF6O3S and a molecular weight of 404.71 g/mol.
The molecular framework of 3-(3,5-Bis(trifluoromethyl)phenoxy)benzenesulfonyl chloride (C14H7ClF6O3S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-(3,5-Bis(trifluoromethyl)phenoxy)benzenesulfonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H7ClF6O3S |
| Molecular Weight | 404.71 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Related Bis Standards
- 4-(3,5-Bis(trifluoromethyl)phenoxy)benzenesulfonylchloride (CAS 885950-90-3)
- 9-Methyl-2-((3-(trifluoromethyl)benzyl)thio)-5H-thiochromeno[4,3-d]pyrimidine (CAS 478246-84-3)
- 2-({[3,5-bis(trifluoromethyl)phenyl]methyl}sulfanyl)-5-phenyl-1,3,4-oxadiazole (CAS 477846-66-5)
- 3-[3,5-Bis(trifluoromethyl)phenyl]-5-[2-(methylsulfanyl)phenyl]-1,2,4-oxadiazole (CAS 339099-68-2)
- (2-Methyl-5-(3-(trifluoromethyl)benzamido)phenyl)boronic acid pinacol ester, 97% (CAS 876322-58-6)
- 4-(4-(4-(Trifluoromethyl)phenyl)thiazol-2-yl)benzenesulfonyl chloride (CAS 446883-84-7)
- (E)-2-((2-((3-(trifluoromethyl)benzyl)oxy)naphthalen-1-yl)methylene)hydrazine-1-carbothioamide (CAS 866138-16-1)
- 1,2-Bis(trifluoromethyl)-3-(difluoromethoxy)-4-iodobenzene (CAS 1804892-36-1)
Recommended Standards
- 5-Bromo-N-(2-chlorobenzyl)-2-ethoxybenzenesulfonamide (CAS 1808720-14-0)
- 3β-tert-Butyldimethylsilyloxy Epiandrosterone (1.0mg/ml in Acetonitrile) (CAS 57711-44-1)
- Bis(acetato)(1,10-phenanthroline)palladium (CAS 35679-81-3)
- Bis(2-cyclohexylethyl)diphenylsilane (CAS 18848-56-1)
- 2-Allylbenzenesulfonamide (CAS 291514-04-0)
- 2-(2-Trifluoromethyl-benzoimidazol-1-yl)-propionic acid hydrochloride (CAS 1219422-80-6)
- 2-Chloro-1-(2-(2-chlorophenyl)-1h-indol-3-yl)ethan-1-one (CAS 924252-37-9)
- 2-Amino-2-(4-chloro-3-fluorophenyl)acetonitrile (CAS 1239611-03-0)
- trans-2,6-Diethyl-4-oxo-piperidine-1-carboxylic acid tert-butyl ester (CAS 1003843-31-9)
- Tucatinib Impurity 42 (CAS CATO-C4X-260542)
- 3-{[(4-fluorophenyl)sulfanyl]methyl}-2H,3H,5H-[1,3]thiazolo[2,3-b]quinazolin-5-one (CAS 477855-97-3)
- 2-(5-Benzyl-4H-1,2,4-triazol-3-yl)acetic acid hydrochloride (CAS 1187927-29-2)
- tert-Butyl (6-formylpyridin-2-yl)carbamate (CAS 956523-98-1)
- Peptide Impurity 82 (CAS 10491-78-8)
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