3-Hydroxy-2-(1H-indol-3-yl)butanoic acid CAS 88612-59-3
| CAS No. | 88612-59-3 |
| Molecular Formula | C12H13NO3 |
| Molecular Weight | 219.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-Hydroxy-2-(1H-indol-3-yl)butanoic acid (CAS 88612-59-3) is a high-purity analytical reference standard with the molecular formula C12H13NO3 and a molecular weight of 219.24 g/mol.
3-Hydroxy-2-(1H-indol-3-yl)butanoic acid (C12H13NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H13NO3 |
| Molecular Weight | 219.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Nitrogen Atoms | 1 |
Related Hydroxy Standards
- Ethyl 3-hydroxy-5-methyl-1H-indole-2-carboxylate (CAS 1060803-17-9)
- 3-Hydroxy-1-isobutylpyrido[2,3-b]pyrazin-2(1H)-one (CAS 1443285-87-7)
- Ethyl 3-hydroxy-4-methyl-1H-indole-2-carboxylate (CAS 153501-38-3)
- 7-Hydroxy-3-methyl-1H,3H,3aH,4H,5H-[1,3]oxazolo[3,4-a]quinolin-1-one (CAS 1824633-17-1)
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- (S)-2-(4-Hydroxy-2-butyl)isoindoline-1,3-dione (CAS 545376-10-1)
- 1-Ethyl-5-hydroxy-2-methyl-1h-indole-3-carboxylic acid (CAS 38189-61-6)
- 2-(1-Hydroxy-2-methylpropan-2-yl)-2,3-dihydro-1h-isoindole-1,3-dione (CAS 4490-74-8)
Recommended Standards
- 3-Hydroxy-1-methyl-3-(2-oxopropyl)indolin-2-one (CAS 76325-64-9)
- 3-Hydroxy-5-methyl-3-(2-oxopropyl)indolin-2-one (CAS 76325-70-7)
- 3-Ethoxy-7-methoxyisoquinolin-1(2H)-one (CAS 342894-34-2)
- 3-Methyl-2-(pyrrolo[2,1-f][1,2,4]triazin-6-yl)butanoic acid (CAS 2090551-64-5)
- Methyl 2-((2-cyano-4-(trifluoromethyl)phenyl)thio)benzoate (CAS 477866-75-4)
- Fenarimol Impurity 2 (Triarimol) (CAS 26766-27-8)
- Ethyl 3-formyl-6-methyl-1H-indole-2-carboxylate (CAS 137076-25-6)
- (S)-1-(Quinolin-4-yl)ethanamine (CAS 255062-65-8)
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