Ethyl 3-iodo-6-nitroimidazo[1,2-a]pyridine-2-carboxylate CAS 886363-76-4
| CAS No. | 886363-76-4 |
| Molecular Formula | C10H8IN3O4 |
| Molecular Weight | 361.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ethyl 3-iodo-6-nitroimidazo[1,2-a]pyridine-2-carboxylate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Ethyl 3-iodo-6-nitroimidazo[1,2-a]pyridine-2-carboxylate (CAS 886363-76-4), molecular formula C10H8IN3O4 and molecular weight 361.09 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Ethyl 3-iodo-6-nitroimidazo[1,2-a]pyridine-2-carboxylate (C10H8IN3O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H8IN3O4 |
| Molecular Weight | 361.09 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 3 |
Related Ethyl Standards
- 3-Iodo-8-nitro-imidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester (CAS 885271-48-7)
- Ethyl 3-iodo-5-nitroimidazo[1,2-a]pyridine-2-carboxylate (CAS 885281-38-9)
- 4-[(4-Iodo-3,5-dimethyl-1H-pyrazol-1-yl)methyl]-5-methylisoxazole-3-carboxylic acid (CAS 1172991-33-1)
- Ethyl 5-iodo-2-morpholinobenzoate (CAS 1131587-28-4)
- Methyl 5-iodo-2-(morpholinomethyl)benzoate (CAS 1131587-42-2)
- Ethyl 3-iodo-4-morpholinobenzoate (CAS 1131614-88-4)
- 3-Iodo-4-pivalamidobenzoic acid (CAS 139078-63-0)
- 1-Benzyl-5-iodo-4-phenyl-1H-1,2,3-triazole (CAS 860002-66-0)
Recommended Standards
- 1-Bromo-11-iodoundecane (CAS 139123-69-6)
- (4-(n-(4-(Trifluoromethoxy)phenyl)sulfamoyl)phenyl)boronic acid (CAS 957062-98-5)
- 1,3-Dichloro-2-(2,6-difluoro-4-(trifluoromethyl)phenoxy)-5-fluorobenzene (CAS 2244084-83-9)
- Ethyl 6-fluoro-4-hydroxy-8-iodoquinoline-3-carboxylate (CAS 1171925-75-9)
- 2-Chloro-N-((5-(4-chlorophenyl)furan-2-yl)methyl)acetamide (CAS 851814-17-0)
- Tetracaine Impurity 3 (CAS 2169-41-7)
- 1-(4-Chloro-3-fluorobenzyl)-1H-pyrazol-4-ol (CAS 1696437-91-8)
- {4-[(3-Imidazol-1-yl-propylamino)-methyl]-phenyl}-dimethyl-amine hydrochloride (CAS 1158457-35-2)
- N-Boc-trans-4-amino-L-proline methyl ester HCl salt (CAS 334999-32-5)
- 1-(4-(Isopentyloxy)-2-methylphenyl)ethan-1-one (CAS 1443346-73-3)
- (1-Phenethylpiperidin-3-yl)methanamine (CAS 725212-69-1)
- Quetiapine Impurity N3 (CAS 102893-57-2)
- 3,4-Di-tert-butoxyphenol (CAS 1243395-09-6)
- Endo-Pro36-Tirzepatide (CAS CATO-CPTD788688)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com