3-Iodo-8-nitro-imidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester CAS 885271-48-7
| CAS No. | 885271-48-7 |
| Molecular Formula | C10H8IN3O4 |
| Molecular Weight | 361.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-Iodo-8-nitro-imidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester (CAS 885271-48-7) is a high-purity analytical reference standard with the molecular formula C10H8IN3O4 and a molecular weight of 361.09 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution, 3-Iodo-8-nitro-imidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 361.09 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 3-Iodo-8-nitro-imidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8IN3O4 |
| Molecular Weight | 361.09 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 3 |
Related Iodo Standards
- Ethyl 3-iodo-5-nitroimidazo[1,2-a]pyridine-2-carboxylate (CAS 885281-38-9)
- Ethyl 3-iodo-6-nitroimidazo[1,2-a]pyridine-2-carboxylate (CAS 886363-76-4)
- 4-[(4-Iodo-3,5-dimethyl-1H-pyrazol-1-yl)methyl]-5-methylisoxazole-3-carboxylic acid (CAS 1172991-33-1)
- Ethyl 5-iodo-2-morpholinobenzoate (CAS 1131587-28-4)
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